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首页> 外文期刊>AIDS care. >'It's about my life': facilitators of and barriers to isoniazid preventive therapy completion among people living with HIV in rural South Africa
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'It's about my life': facilitators of and barriers to isoniazid preventive therapy completion among people living with HIV in rural South Africa

机译:“这是关于我的生活”:促进者和障碍的障碍,在南非农村艾滋病毒患者中的人们完成

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Despite the recent rollout of Isoniazid Preventive Therapy (IPT) to prevent TB in people living with HIV in South Africa, adherence and completion rates are low. To explore barriers to IPT completion in rural KwaZulu-Natal, South Africa, we conducted individual semi-structured interviews among 30 HIV patients who had completed or defaulted IPT. Interview transcripts were analyzed according to the framework method of qualitative analysis. Facilitators of IPT completion included knowledge of TB and IPT, accepting one's HIV diagnosis, viewing IPT as similar to antiretroviral therapy, having social support in the community and the clinic, trust in the healthcare system, and desire for health preservation. Barriers included misunderstanding of IPT's preventive role in the absence of symptoms, inefficient health service delivery, ineffective communication with healthcare workers, financial burden of transport to clinic and lost wages, and competing priorities. HIV-related stigma was not identified as a significant barrier to IPT completion, and participants felt confident in their ability to manage stigma, for example by pretending their medications were for unrelated conditions. Completers were more comfortable communicating with health care workers than were defaulters. Efforts to facilitate successful IPT completion must include appropriate counseling and education for individual patients and addressing inefficiencies within the health care system in order to minimize patients' financial and logistical burden. These patient-level and structural changes are necessary for IPT to successfully reduce TB incidence in this resource-limited setting.
机译:尽管最近的Isoniazid预防疗法(IPT)推出了预防南非艾滋病毒的人民,但坚持和完成率较低。为了探讨南非昆祖鲁 - 纳塔尔省农村地区的IPT完成的障碍,我们在30名已完成或违约的患者中进行了个体半结构化访谈。根据定性分析的框架方法分析了采访转录物。 IPT完成的促进者包括TB和IPT的知识,接受一个人的艾滋病病毒诊断,观察IPT与抗逆转录病毒治疗相似,在社区中具有社会支持以及诊所,信任医疗保健系统,以及保健的渴望。障碍包括对IPT在没有症状的预防作用的误解,效率低下的卫生服务,与医疗工作者的无效沟通,运输到诊所和工资的财务负担以及竞争优先事项。与IPT完成的艾滋病毒相关耻辱没有被确定为一个重要的屏障,参与者对他们管理耻辱的能力感到充满信心,例如通过假装他们的药物是不相关的条件。完成者比违规者更舒适地沟通。促进成功IPT完成的努力必须包括对个别患者的适当咨询和教育,并解决医疗保健系统内的低效率,以尽量减少患者的财务和后勤负担。这些患者水平和结构性变化是在该资源限制环境中成功降低结核病发病的必要条件。

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