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首页> 外文期刊>AIDS Research and Human Retroviruses >Assessment of Microcirculation in HIV-Positive Patients with a Noninvasive Method: Nailfold Videocapillaroscopy
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Assessment of Microcirculation in HIV-Positive Patients with a Noninvasive Method: Nailfold Videocapillaroscopy

机译：艾滋病毒阳性患者的微循环评估非侵入性方法：钉子玻璃瘤

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Chronic inflammation that contributes to the deterioration of the mechanical form of both the vascular wall and the function of endothelial has been shown to cause vascular dysfunction in patients with human immunodeficiency virus (HIV). Nailfold videocapillaroscopy (NVC) is a noninvasive and simple technique used to analyze dermal microvasculature. The aims of our study were to detect the morphological and functional properties of microcirculation in HIV-positive patients utilizing NVC and to compare the results with those obtained from healthy individuals and investigate whether these changes had supported any correlation with HIV. In this prospective study, 51 male HIV-positive patients were the subjects and 59 male healthy individuals made up the control group. Capillaroscopic findings, obtained from both groups by NVC, were evaluated. Tortuosity, a capillaroscopic finding, was significantly higher in the group with HIV (p < .001). In logistic regression analysis, tortuosity [odds ratio (OR), 4.658; p = .001], bizarre capillary (OR, 1.733; p = .319), and capillary ectasia (OR, 0.867; p = .493) were considered significant. The changes of capillaroscopic findings were found to be correlated with HIV. We suggest videocapillaroscopy in the evaluation of microvascular changes in HIV patients, as a dependable contributing method.
机译：慢性炎症有助于血管壁的机械形式的恶化和内皮的功能已经显示出人类免疫缺陷病毒（HIV）患者血管功能障碍。钉子录像机镜检查（NVC）是一种用于分析皮肤微血管结构的非侵入性和简单的技术。我们的研究目的是检测利用NVC的艾滋病毒阳性患者微循环的形态学和功能性，并将结果与​​从健康个体获得的结果进行比较，研究这些变化是否支持与艾滋病毒的任何相关性。在这项前瞻性研究中，51名雄性艾滋病毒阳性患者是受试者，59名男性健康个体组成对照组。评估由NVC的两组获得的毛细管镜检查。曲折性，毛细血管镜检查，患有HIV的组显着高（P <.001）。在Logistic回归分析中，曲折度[赔率比（或），4.658; p = .001]，奇异毛细血管（或1.733; p = .319），和毛细管异位（或0.867; p = .493）被认为是显着的。发现毛细管镜检查的变化与艾滋病毒相关。我们建议在艾滋病毒患者微血管变化评估中的录像机镜，作为可靠的贡献方法。

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