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首页> 外文期刊>AIDS Research and Human Retroviruses >Three-Year Durability of Immune Responses Induced by HIV-DNA and HIV-Modified Vaccinia Virus Ankara and Effect of a Late HIV-Modified Vaccinia Virus Ankara Boost in Tanzanian Volunteers
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Three-Year Durability of Immune Responses Induced by HIV-DNA and HIV-Modified Vaccinia Virus Ankara and Effect of a Late HIV-Modified Vaccinia Virus Ankara Boost in Tanzanian Volunteers

机译:HIV-DNA和HIV改性痘苗病病毒Ankara诱导的免疫应答的三年耐久性及坦桑尼亚志愿者晚期艾滋病毒改性痘苗病毒Ankara提升的效果

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摘要

p ? p ? p ?=?.064 and p ?=?.002, respectively. In conclusion, the HIV-DNA prime/HIV-MVA boost regimen elicited potent antibody and cellular immune responses with remarkable durability, and a third HIV-MVA immunization significantly boosted both antibody and cellular immune responses relative to the levels detected at the time of the third HIV-MVA, but not to higher levels than after the second HIV-MVA.]]>
机译:P? P? p?= ?. 064和p?= 002。 总之,HIV-DNA PRIME / HIV-MVA升压方案引发了有效的抗体和细胞免疫应答,具有显着耐久性,并且第三个HIV-MVA免疫显着提高了相对于当时检测到的水平的抗体和细胞免疫应答。 第三个HIV-MVA,但不是比第二个HIV-MVA之后更高的水平。]>

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  • 作者单位

    Department of Microbiology and Immunology Muhimbili University of Health and Allied Sciences;

    Department of Internal Medicine Muhimbili University of Health and Allied Sciences (MUHAS) Dar es;

    Department of Microbiology Tumor and Cell Biology Karolinska Institutet Stockholm Sweden.;

    Department of Internal Medicine Muhimbili University of Health and Allied Sciences (MUHAS) Dar es;

    Department of Microbiology and Immunology Muhimbili University of Health and Allied Sciences;

    Department of Microbiology and Immunology Muhimbili University of Health and Allied Sciences;

    Public Health Agency of Sweden Solna Sweden.;

    Department of Microbiology Tumor and Cell Biology Karolinska Institutet Stockholm Sweden.;

    Viral Evolution and Transmission Unit Division of Immunology Transplantation and Infectious;

    The Military HIV Research Program The Henry M. Jackson Foundation for the Advancement of Military;

    National Institute of Allergy and Infectious Diseases (NIAID)/National Institutes of Health (NIH);

    National Institute of Allergy and Infectious Diseases (NIAID)/National Institutes of Health (NIH);

    Department of Microbiology Tumor and Cell Biology Karolinska Institutet Stockholm Sweden.;

    Department of Microbiology and Immunology Muhimbili University of Health and Allied Sciences;

    Department of Surgery and Molecular Genetics and Microbiology Duke University Medical Center;

    Venh?lsan Karolinska Institutet S?dersjukhuset Stockholm Sweden.;

    Department of Microbiology Tumor and Cell Biology Karolinska Institutet Stockholm Sweden.;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 传染病;
  • 关键词

    HIV; vaccine; DNA; MVA; immune response;

    机译:艾滋病毒;疫苗;DNA;增值税;免疫反应;

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