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HIV Care Among Elderly Population: Systematic Review and Meta-Analysis

机译：老年人口中的艾滋病毒护理：系统评价和荟萃分析

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摘要

Elderly people living with HIV are increasing. At present in the United States, nearly half of newly diagnosed HIV-infected people are aged >50 years. Diagnosis and treatment of HIV-infected elderly patients tends to be delayed by several health care factors as several life-threatening diseases are common in elderly people. This study aimed to find the pooled HIV prevalence in elderly population and the present situation of continuum care for the elderly HIV patients through systematic review and meta-analysis. All previously published articles from 2000 to 2018 are retrieved using MEDLINE, PUBMED, Cochrane Library, EMBASE, and Google Scholar. DerSimonian and Laird Random Effects model are used to critically appraise articles. STATA 13.0 is used to perform the meta-analysis and quantum-geographic information system (Q-GIS) is used to prepare desired map. I-2 statistics has been used to test heterogeneity and publication biases. Results have been presented using forest plots. A total of 28 studies are included in this meta-analysis. Present analysis revealed pooled prevalence of HIV in elderly population as 15.79% with a lower rate of viral suppression as 11.524% (95% confidence interval, CI: 11.199-11.855), where a moderate number 38.643% (95% CI: 38.289-38.997) of elderly patients received antiretroviral therapy (ART) globally. The ART retention rate was 12.769% (95% CI: 12.540-13.001) with 6.15% (95% CI: 6.089-6.212) mortality. Despite successful administration of ART in developing part of the world that have relatively higher retention rates among HIV-infected elderly patients only a small percentage are virally suppressed, largely due to elderly drugs interact with ART and several comorbidities reduce the life span of the elderly people.
机译：艾滋病毒的老年人正在增加。目前在美国，近一半的新诊断的艾滋病毒感染者年龄较大> 50年。艾滋病毒感染的老年患者的诊断和治疗趋于几种卫生保健因素延迟，因为几种危及生命的疾病在老年人中常见。本研究旨在通过系统审查和荟萃分析发现老年人人口的群体HIV患病率和老年人HIV患者的现状。使用Medline，PubMed，Cochrane Library，Embase和Google Scholar检索来自2000年至2018年的此前发表的文章。狄奥尼昂和莱尔德随机效应模型用于批判性评估文章。 STATA 13.0用于执行元分析和量子 - 地理信息系统（Q-GIS）来准备所需的地图。 I-2统计数据已被用于测试异质性和出版物偏见。结果已经使用森林图呈现。该荟萃分析中共有28项研究。目前的分析显示，老年人人口中的艾滋病毒血液普及为15.79％，病毒抑制率较低为11.524％（95％置信区间，CI：11.199-11.855），其中38.643％（95％CI：38.289-38.997 ）老年患者在全球接受抗逆转录病毒治疗（艺术）。艺术保留率为12.769％（95％CI：12.540-13.001），6.15％（95％CI：6.089-6.212）死亡率。尽管在艾滋病毒感染的老年患者中具有相对较高的保留率的世界中成功的艺术行长，但只有小百分比是公然抑制的，大部分是由于老年人与艺术和几种合并症互动，减少了老年人的寿命。

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