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首页> 外文期刊>Alcoholism: Clinical and experimental research >Intelligence Test Scores Before and After Alcohol-Related Disorders-A Longitudinal Study of Danish Male Conscripts
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Intelligence Test Scores Before and After Alcohol-Related Disorders-A Longitudinal Study of Danish Male Conscripts

机译：智力测试评分在酒精相关的疾病之前和之后 - 丹麦男性应征的纵向研究

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Background Existing studies on intellectual consequences of alcohol-related disorders are primarily cross-sectional and compare intelligence test scores of individuals with and without alcohol-related disorders, hence mixing the influence of alcohol-related disorders and predisposing factors such as premorbid intelligence. In this large-scale study, the primary aim was to estimate associations of alcohol-related disorders with changes in intelligence test scores from early adulthood to late midlife. Methods Data were drawn from a follow-up study on middle-aged men, which included a re-examination of the same intelligence test as completed in young adulthood at military conscription (total analytic sample = 2,499). Alcohol-related hospital diagnoses were obtained from national health registries, whereas treatment for alcohol problems was self-reported at follow-up. The analyses included adjustment for year of birth, retest interval, baseline intelligence quotient (IQ) score, education, smoking, alcohol consumption, and psychiatric and somatic comorbidity. Results Individuals with alcohol-related hospital diagnoses (8%) had a significantly lower baseline IQ score (95.0 vs. 100.5, p < 0.001) and a larger decline in IQ scores from baseline to follow-up (-8.5 vs. -4.8, p < 0.001) than individuals without such diagnoses. The larger decline in IQ scores with alcohol-related hospital diagnoses remained statistically significant after adjustment for all the covariates. Similar results were revealed when IQ scores before and after self-reported treatment for alcohol problems (10%) were examined. Conclusions Individuals with alcohol-related disorders have a lower intelligence test score both in young adulthood and in late midlife, and these disorders, moreover, seem to be associated with more age-related decline in intelligence test scores. Thus, low mean intellectual ability observed in individuals with alcohol-related disorders is probably a result of both lower premorbid intelligence and more intellectual decline.
机译：背景技术现有的饮酒相关疾病的智力后果研究主要是横截面和比较有没有酒精相关疾病的个体的智力测试评分，因此混合了酒精相关疾病的影响和预感因子如前膜智能。在这种大规模的研究中，主要目的是估算酒精相关疾病的关联与年初已于年初中午的智力考试成绩的变化。方法从中年男性的后续研究中汲取数据，其中包括重新检查与军事征兵的年轻成年期间已完成的相同智力测试（总分析样本= 2,499）。与国家卫生登记处获得酗酒相关的医院诊断，而在随访中则自我报告酒精问题的治疗。分析包括诞生年份的调整，重新测试间隔，基线情报商（IQ）得分，教育，吸烟，酒精消费和精神疗法和体细胞合并症。结果与酒精相关医院诊断（8％）的个体具有显着较低的基线IQ评分（95.0 vs.100.5，P <0.001），从基线到后续行动的智商分数较大（-8.5 Vs. -4.8， P <0.001）比没有这种诊断的个体。在调整所有协变者后，含有酒精相关医院诊断的智商分数较大的差异仍然存在统计学意义。当研究了对酒精问题的自我报告治疗之前和之后的智商评分（10％）之前和之后，揭示了类似的结果。结论含有酒精相关疾病的个体在年轻的成年和晚期中，智力测试分数较低，而且这些障碍似乎与智力考试成绩的更年龄相关的下降相关。因此，在有醇类相关疾病的个体中观察到的低平均智力能力可能是较低过早智力和更具智力下降的结果。

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