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An experimental investigation of interfacial instability in separated blood

机译:分离血液界面不稳定性的实验研究

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Experiments are done with separated human blood decelerated at constant rates to determine the maximum deceleration rate while avoiding remixing of the layers, which have different densities and viscosities. The deceleration rate affects both the stability and separation of particles through sedimentation. The velocity at onset of instability for a constant deceleration rate is experimentally determined for a 12-cm-diameter disk. Parameters of cell pack thickness, plasma thickness, and total thickness are investigated experimentally, and the only statistically significant parameter to affect stability is rate of deceleration. The data describe a correlation separating regions of stability and instability. To understand stability in decelerating flow of separated blood plasma and cells, the equations of motion are solved for a two-layer fluid flow with a moving boundary and free surface. Inclusion of non-Newtonian rheology of blood predicts large discontinuities in the shear rate, which is proposed as the cause of the interfacial instabilities. (c) 2019 American Institute of Chemical Engineers AIChE J, 65: 1376-1386, 2019
机译:在恒定速率下减速的分离的人血液进行实验,以确定最大减速速率,同时避免具有不同密度和粘度的层的复合。减速率通过沉降影响粒子的稳定性和分离。对恒定减速率的不稳定性发作的速度是针对12cm-直径的盘进行实验确定的。实验研究了细胞包装厚度,等离子体厚度和总厚度的参数,并且影响稳定性的唯一统计学意义的参数是减速率。数据描述了稳定性和不稳定性的相关分离区域。为了了解分离血浆和电池的减速流动的稳定性,求解运动方程,用于具有移动边界和自由表面的双层流体流动。纳入血液的非牛顿流变学预测剪切速率的大不连续性,这是作为界面不稳定性的原因。 (c)2019年美国化学工程师研究所Aiche J,65:1376-1386,2019

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