HIV-1 superinfection with a triple-class drug-resistant strain in a patient successfully controlled with antiretroviral treatment

CastroE.; ZhaoH.; CavassiniM.; MullinsJ.I.; PantaleoG.; BartP.-A.

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HIV-1 superinfection with a triple-class drug-resistant strain in a patient successfully controlled with antiretroviral treatment

机译：HIV-1具有三类耐药菌株的耐药菌株，患者成功控制抗逆转录病毒治疗

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We report a case of HIV-1 superinfection (HSI) with a clade B, triple-class resistant virus in a patient successfully controlling viremia with continuous combination antiretroviral therapy started 8 years earlier during primary HIV infection. The course of HIV infection prior to HSI was monitored in both the source partner and recipient (8 and 11 years, respectively) and 4 years following HSI. This case report demonstrates re-infection with HIV-1 despite effective combination antiretroviral therapy.

机译：我们在患者中举报了具有Clade B的HIV-1超染色（HSI）的案例，在患者中成功控制病毒血症，在原发性艾滋病毒感染前8年来8年前开始患者。 HSI之前的HIV感染课程在源合作伙伴和收件人（分别为8和11年）和HSI后4年内监测。尽管有效的组合抗逆转录病毒治疗，但这种情况报告表明，尽管有效的组合抗逆转录病毒治疗，但表明患有HIV-1的再感染。

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来源
《AIDS》 |2014年第12期|共5页
作者
CastroE.; ZhaoH.; CavassiniM.; MullinsJ.I.; PantaleoG.; BartP.-A.;
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作者单位

Service of Community Psychiatry Centre Hospitalier Universitaire Vaudois University of Lausanne;

Departments of Microbiology Medicine and Laboratory Medicine University of Washington School of;

Service of Community Psychiatry Centre Hospitalier Universitaire Vaudois University of Lausanne;

Departments of Microbiology Medicine and Laboratory Medicine University of Washington School of;

Laboratory of AIDS Immunopathogenesis Service of Immunology and Allergy Swaziland;

Laboratory of AIDS Immunopathogenesis Service of Immunology and Allergy Swaziland Service of;

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正文语种 eng
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1. HIV-1 superinfection with a triple-class drug-resistant strain in a patient successfully controlled with antiretroviral treatment [J] . CastroE., ZhaoH., CavassiniM., AIDS . 2014,第12期

机译：成功通过抗逆转录病毒治疗控制的患者中的HIV-1双重感染三重耐药菌株
2. HIV-1 integrase sequence variability in antiretroviral naive patients and in triple-class experienced patients subsequently treated with raltegravir. [J] . Varghese V, Liu TF, Rhee SY, AIDS Research and Human Retroviruses . 2010,第12期

机译：天真抗逆转录病毒患者和随后接受拉格列韦治疗的三级有经验患者的HIV-1整合酶序列变异性。
3. High prevalence of genotypic and phenotypic HIV-1 drug-resistant strains among patients receiving antiretroviral therapy in Abidjan, Cote d'Ivoire. [J] . Adje C, Cheingsong R, Roels TH, JAIDS: Journal of acquired immune deficiency syndromes . 2001,第5期

机译：在科特迪瓦阿比让接受抗逆转录病毒治疗的患者中，基因型和表型HIV-1耐药株的患病率较高。
4. Uncertainty quantification for a model of HIV-1 patient response to antiretroviral therapy interruptions [C] . Baraldi Robert, Cross Karissa, McChesney Christina, American Control Conference . 2014

机译：HIV-1患者抗逆转录病毒治疗中断反应模型的不确定度量化
5. Persistence of HIV-1 despite highly active antiretroviral therapy (HAART) and immune responses: Evidence for a novel viral reservoir in patients on HAART and characterization of HIV-1 virus and immune responses in elite suppressors. [D] . Bailey, Justin R. 2007

机译：尽管有高活性的抗逆转录病毒疗法（HAART）和免疫应答，但HIV-1仍持续存在：有证据表明在HAART患者中出现了新型病毒库，并且有关于HIV-1病毒和精英抑制者免疫应答的特征。
6. HIV-1 Integrase Sequence Variability in Antiretroviral Naïve Patients and in Triple-Class Experienced Patients Subsequently Treated with Raltegravir [O] . Vici Varghese, Tommy F. Liu, Soo-Yon Rhee, -1

机译：HIV-1整合酶序列变异性在抗逆转录病毒初治患者和三级有经验的患者中随后接受拉格达韦治疗
7. HIV-1 superinfection with a triple-class drug-resistant strain in a patient successfully controlled with antiretroviral treatment. [O] . Castro, E., Zhao, H., Cavassini, M., 2014

机译：在通过抗逆转录病毒治疗成功控制的患者中，HIV-1感染带有三级耐药菌株。

HIV-1 superinfection with a triple-class drug-resistant strain in a patient successfully controlled with antiretroviral treatment

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