HIV-1 superinfection with a triple-class drug-resistant strain in a patient successfully controlled with antiretroviral treatment

CastroE.; ZhaoH.; CavassiniM.; MullinsJ.I.; PantaleoG.; BartP.-A.

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HIV-1 superinfection with a triple-class drug-resistant strain in a patient successfully controlled with antiretroviral treatment

机译：成功通过抗逆转录病毒治疗控制的患者中的HIV-1双重感染三重耐药菌株

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We report a case of HIV-1 superinfection (HSI) with a clade B, triple-class resistant virus in a patient successfully controlling viremia with continuous combination antiretroviral therapy started 8 years earlier during primary HIV infection. The course of HIV infection prior to HSI was monitored in both the source partner and recipient (8 and 11 years, respectively) and 4 years following HSI. This case report demonstrates re-infection with HIV-1 despite effective combination antiretroviral therapy.

机译：我们报告了一例HIV-1超级感染（HSI）的进化枝B型三重抗药性病毒，该患者在初次HIV感染早期就开始了连续8年的抗逆转录病毒疗法的连续联合成功控制病毒血症。在源性伴侣和接受者（分别为8和11年）和HSI之后的4年中，对HSI之前的HIV感染过程进行了监测。该病例报告表明尽管进行了有效的抗逆转录病毒疗法联合治疗，HIV-1仍被再次感染。

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《AIDS》 |2014年第12期|共5页
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CastroE.; ZhaoH.; CavassiniM.; MullinsJ.I.; PantaleoG.; BartP.-A.;
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正文语种 eng
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1. HIV-1 superinfection with a triple-class drug-resistant strain in a patient successfully controlled with antiretroviral treatment [J] . CastroE., ZhaoH., CavassiniM., AIDS . 2014,第12期

机译：成功通过抗逆转录病毒治疗控制的患者中的HIV-1双重感染三重耐药菌株
2. HIV-1 integrase sequence variability in antiretroviral naive patients and in triple-class experienced patients subsequently treated with raltegravir. [J] . Varghese V, Liu TF, Rhee SY, AIDS Research and Human Retroviruses . 2010,第12期

机译：天真抗逆转录病毒患者和随后接受拉格列韦治疗的三级有经验患者的HIV-1整合酶序列变异性。
3. High prevalence of genotypic and phenotypic HIV-1 drug-resistant strains among patients receiving antiretroviral therapy in Abidjan, Cote d'Ivoire. [J] . Adje C, Cheingsong R, Roels TH, JAIDS: Journal of acquired immune deficiency syndromes . 2001,第5期

机译：在科特迪瓦阿比让接受抗逆转录病毒治疗的患者中，基因型和表型HIV-1耐药株的患病率较高。
4. Uncertainty quantification for a model of HIV-1 patient response to antiretroviral therapy interruptions [C] . Baraldi Robert, Cross Karissa, McChesney Christina, American Control Conference . 2014

机译：HIV-1患者抗逆转录病毒治疗中断反应模型的不确定度量化
5. Persistence of HIV-1 despite highly active antiretroviral therapy (HAART) and immune responses: Evidence for a novel viral reservoir in patients on HAART and characterization of HIV-1 virus and immune responses in elite suppressors. [D] . Bailey, Justin R. 2007

机译：尽管有高活性的抗逆转录病毒疗法（HAART）和免疫应答，但HIV-1仍持续存在：有证据表明在HAART患者中出现了新型病毒库，并且有关于HIV-1病毒和精英抑制者免疫应答的特征。
6. HIV-1 Integrase Sequence Variability in Antiretroviral Naïve Patients and in Triple-Class Experienced Patients Subsequently Treated with Raltegravir [O] . Vici Varghese, Tommy F. Liu, Soo-Yon Rhee, -1

机译：HIV-1整合酶序列变异性在抗逆转录病毒初治患者和三级有经验的患者中随后接受拉格达韦治疗
7. HIV-1 superinfection with a triple-class drug-resistant strain in a patient successfully controlled with antiretroviral treatment. [O] . Castro, E., Zhao, H., Cavassini, M., 2014

机译：在通过抗逆转录病毒治疗成功控制的患者中，HIV-1感染带有三级耐药菌株。

HIV-1 superinfection with a triple-class drug-resistant strain in a patient successfully controlled with antiretroviral treatment

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