Temperature and pH Effect on the Polymorphism of Aprotinin(BPTI)in Sodium Bromide Solutions

Stephane Veesler; Natalie Ferte; Marie-Sophie Costes

首页> 外文期刊>Crystal growth & design >Temperature and pH Effect on the Polymorphism of Aprotinin(BPTI)in Sodium Bromide Solutions

【24h】

Temperature and pH Effect on the Polymorphism of Aprotinin(BPTI)in Sodium Bromide Solutions

机译：温度和pH对溴化钠溶液中抑肽酶（BPTI）多态性的影响

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

In this contribution,we present the phase transition of protein crystals in suspension as a function of temperature and pH.We measure the solubility of two polymorphs of aprotinin(BPTI)in 2 M NaBr solutions at different acidic pH values between 4.50 and 5.13 at 20 deg C.We observe a major increase in solubility when the pH is increased from 4.5 to 5.13.The temperature effect between 5 and 35 deg C on the solubility of the two BPTI polymorphs in 2 M NaBr solutions is investigated at pH 4.5 and 4.75.We observe two polymorphs in the same solution with direct and reverse solubility curves.We show that an adequate control of temperature around the transition temperature between the two polymorphs can be used to obtain the polymorph desired.

机译：在这项贡献中，我们提出了悬浮液中蛋白质晶体的相变随温度和pH的变化。我们测量了抑肽酶（BPTI）的两种多晶型物在2 M NaBr溶液中在20至4.50和5.13之间的不同酸性pH值下的溶解度pH值从4.5增加到5.13时，我们观察到溶解度显着增加。在pH值为4.5和4.75的情况下，研究了温度在5到35摄氏度之间对两种BPTI多晶型物在2 M NaBr溶液中的溶解度的影响。我们在同一溶液中观察到两个多晶型物具有正向和反向的溶解度曲线，表明可以在两个多晶型物之间的转变温度附近适当控制温度，从而获得所需的多晶型物。

著录项

来源
《Crystal growth & design》 |2004年第6期|共5页
作者
Stephane Veesler; Natalie Ferte; Marie-Sophie Costes;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类晶体学;
关键词

相似文献

外文文献
中文文献
专利

1. Temperature and pH Effect on the Polymorphism of Aprotinin(BPTI)in Sodium Bromide Solutions [J] . Stephane Veesler, Natalie Ferte, Marie-Sophie Costes Crystal growth & design . 2004,第6期

机译：温度和pH对溴化钠溶液中抑肽酶（BPTI）多态性的影响
2. The vapour pressures of saturated aqueous solutions of sodium chloride, sodium bromide, sodium nitrate, sodium nitrite, potassium iodate, and rubidium chloride at temperatures from 227 K to 323 K [J] . Apelblat A., Korin E. The Journal of Chemical Thermodynamics . 1998,第1期

机译：在227 K至323 K的温度下，氯化钠，溴化钠，硝酸钠，亚硝酸钠，碘酸钾和氯化rub的饱和水溶液的蒸气压
3. Isopiestic Studies on the Quaternary System (Water + Ethanol + Sodium Bromide + Ammonium Bromide) at the Temperature 298.15 K: Comparison with the Ideal-Like Solution Model [J] . Mei Wang, Zhi-Chang Wang Journal of Chemical and Engineering Data: the ACS Journal for Data . 2009,第2期

机译：298.15 K温度下四元体系（水+乙醇+溴化钠+溴化铵）的同构研究：与理想溶液模型比较
4. Study on Flotation Separation and Determination of Mercury (II) by Sodium Bromide-Ammonium Thiocyanate-Octadecyl Trimethyl ammonium Bromide System [C] . Changqing Tu, Xinrong Wen International Conference on Chemical Engineering and Advanced Materials . 2012

机译：溴化钠 - 硫氰酸钠 - 十六烷基溴化铵体系浮选分离与汞（II）的浮选分离和测定研究
5. The effect of temperature on galvanically induced hydrolysis of graphite/BMI composite in 3.5 percent sodium chloride solution. [D] . Carter, Harold Wayne. 1992

机译：温度对3.5％氯化钠溶液中石墨/ BMI复合材料的电诱导水解的影响。
6. A second polymorph of sodium dihydrogen citrate NaH2C6H5O7: structure solution from powder diffraction data and DFT comparison [O] . Alagappa Rammohan, James A. Kaduk 2016

机译：柠檬酸二氢钠的第二种多晶型物NaH2C6H5O7：根据粉末衍射数据和DFT比较得到的结构溶液
7. Effects of Sodium Bromide Salt and Temperature on the behaviour of Aqueous Solution of Cetyltrimethylammonium Bromide [O] . Grace A. Cookey, Charles C. Obunwo 2014

机译：溴化钠盐和温度对甲基三甲基溴化物水溶液行为的影响
8. Enthalpies of Dilution of Dodecyl- and Tetradecyl- Trimethylammonium Bromides in Aqueous Solutions of Sodium Bromide at Elevated Temperatures: Topical Report [R] . Lam, A. C. , Archer, D. G. 1988

机译：在高温下溴化钠水溶液中十二烷基 - 和十四烷基 - 三甲基溴化铵的稀释焓：局部报告

Temperature and pH Effect on the Polymorphism of Aprotinin(BPTI)in Sodium Bromide Solutions

摘要

著录项

相似文献

相关主题

期刊订阅