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首页> 外文期刊>Advances in anatomy embryology and cell biology. >The Role of Progesterone in Maternal Recognition of Pregnancy in Domestic Ruminants
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The Role of Progesterone in Maternal Recognition of Pregnancy in Domestic Ruminants

机译：黄体酮在国内反刍动物妊娠孕妇识别的作用

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Progesterone (P4) secretion by the corpus luteum is critical for the establishment and maintenance of pregnancy and plays a major role in regulating endometrial secretions essential for stimulating and mediating changes in conceptus growth and differentiation throughout early pregnancy. Numerous studies have demonstrated an association between elevated P4 and acceleration in conceptus elongation. Given that larger conceptuses produce more interferon tau, the pregnancy recognition signal in ruminants, it would be reasonable to hypothesize that treatments aimed at increasing peripheral concentrations of P4 should improve pregnancy rate. However, data on the impact of post-insemination supplementation of P4 on pregnancy rates are conflicting and, at best, indicate a modest positive response. Whether a P4-induced increase in conceptus size can improve fertility continues to be an active area of investigation. The aim of this chapter is to review recent data on the role of P4 in conceptus development in ruminants, particularly cattle, and to summarize results from attempts at manipulating endogenous P4 with the aim of improving conceptus survival and pregnancy rate.
机译：黄体酮（P4）Corpus Luteum的分泌对妊娠的建立和维持至关重要，并在调节刺激和介导在早期妊娠中升高和分化的变化必然的子宫内膜分泌中发挥重要作用。许多研究表明了升高的P4与概念伸长率的加速之间的关联。鉴于更大的概念产生更多的干扰素TAU，反刍动物中的妊娠识别信号，假设旨在提高P4的外周浓度的治疗应该提高妊娠率。但是，关于妊娠率对P4的授权后的影响的数据的数据是相互冲突的，并且充其量，表明了一个适度的积极反应。 P4诱导的概念尺寸的增加是否可以改善生育能力仍然是一个活跃的调查领域。本章的目的是审查最近关于P4在反刍动物，特别是牛的概念开发中的作用的数据，并概括了操纵内源性P4的尝试结果，目的是提高概念存活和怀孕率。

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