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首页> 外文期刊>Acta Neurochirurgica >Intrasellar plasmacytoma: an unusual presentation of multiple myeloma.
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Intrasellar plasmacytoma: an unusual presentation of multiple myeloma.

机译:浆内浆细胞瘤:多发性骨髓瘤的异常表现。

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INTRODUCTION: Plasmacytomas are unusual causes of a sellar mass. Occasionally, they can be misdiagnosed as a nonfunctioning adenoma because of radiological and clinical similarities. LITERATURE REVIEW: We reviewed the pertinent literature and discuss here in the light of an illustrative case of our own. DISCUSSION: A 70-year-old woman presented with a recurrent hypophysial mass. Initial diagnosis of a nonfunctioning pituitary adenoma was later overruled by a repeat biopsy, which showed a plasmacytoma. The tumor stained positively for CD138 and kappa light chain. Further studies confirmed the diagnosis of multiple myeloma. The patient was successfully treated with radiotherapy followed by systemic chemotherapy. Because they have different therapeutic implications, extramedullary plasmacytomas involving pituitary gland should be considered in the differential diagnosis of a nonfunctioning pituitary mass.
机译:简介:浆细胞瘤是鞍状肿块的异常原因。有时,由于放射学和临床相似性,它们可能会被误诊为无功能的腺瘤。文学评论:我们回顾了相关文献并在此根据我们自己的例证进行讨论。讨论:一名70岁的女性出现了反复的垂体肿块。最初的诊断为无功能的垂体腺瘤后来被重复的活检推翻了,这表明浆细胞瘤。肿瘤对CD138和κ轻链染色阳性。进一步的研究证实了多发性骨髓瘤的诊断。该患者已成功接受放射治疗,随后进行了全身化学疗法。由于它们具有不同的治疗意义,因此在鉴别无功能的垂体瘤时应考虑涉及垂体的髓外浆细胞瘤。

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