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首页> 外文期刊>American journal of dentistry >Effect of oral antimicrobial mouthrinses containing alcohol on viability of Streptococcus mutans and microcosm biofilm and on the prevention of enamel caries lesions
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Effect of oral antimicrobial mouthrinses containing alcohol on viability of Streptococcus mutans and microcosm biofilm and on the prevention of enamel caries lesions

机译：口服抗微生物口含有醇对链球菌和微观体生物膜的活力和搪瓷龋病病毒的影响

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Purpose: To evaluate the effect of PerioGard, Listerine, Noplak, Malvatricin and Cepacol commercial mouthrinses containing alcohol on the viability of Streptococcus mutans strain and of a microcosm biofilm and on the prevention of enamel demineralization. Methods: The minimum inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) were determined against S. mutans (ATCC 25175). Microcosm biofilm formed from human saliva mixed with McBain saliva was created on bovine enamel for 5 days. From the 2nd to the 5th day, the enamel samples were exposed to McBain with 0.2% sucrose and to the mouthrinses (1 x 60 seconds). The biofilm viability was determined by fluorescence and the enamel demineralization by TMR. Results: The lowest MIC and MBC values were observed for Cepacol, while the highest values were found for Listerine. The mouthrinses significantly increased the number of dead bacteria in biofilm, varying from 38.0+11.2% (Noplak) to 58.5 +/- 13.9% (Listerine), compared to control (12.7 +/- 10.6%), except Periogard (30.1 +/- 12.4%). All mouthrinses reduced mineral loss (P 0.0001), but only Noplak and Cepacol were able to significantly reduce lesion depth. Cepacol and Noplak presented the best anti-caries effect under this experimental model.
机译：目的：评估脑膜炎，李斯特氏菌，Noplak，Malvatricin和Cepacol商业口腔含有酒精的效果，含有酒精的菌株和微观液体菌株和预防搪瓷脱矿质的活力。方法：测定对S. mutans（ATCC 25175）测定最小抑制浓度（MIC）和最小杀菌浓度（MBC）。用与McBain唾液混合的人类唾液形成的微观生物膜在牛珐琅上产生5天。从第2天至第5天，搪瓷样品用0.2％蔗糖和口肾上（1×60秒）暴露于McBain。通过TMR通过荧光和牙釉质脱矿质测定生物膜活力。结果：对番茄科醇观察到最低的MIC和MBC值，而发现Listerine的最高值。漱口液显着增加了生物膜的死菌数，与38.0 + 11.2％（Noplak）相加，与Periogard除外（12.7 +/- 10.6％）相比，与58.5 +/- 13.9％（listerine）不同（30.1 +/- 10.6％）（30.1 + / - 12.4％）。所有漱口乳都会降低矿物质损失（P <0.0001），但只能显着降低病变深度的Noplak和Cepacol。 Cepacol和Noplak在这个实验模型下提出了最佳的抗龋效应。

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