Airway basophils are increased and activated in eosinophilic asthma

Suzuki Y.; Wakahara K.; Nishio T.; Ito S.; Hasegawa Y.

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Airway basophils are increased and activated in eosinophilic asthma

机译：气道嗜碱性粒细胞在嗜酸性胃肠中增加和激活

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Background: The impact of basophils on asthma pathogenesis remains largely unexplored, particularly in humans. Here, we evaluated the frequencies and activation status of basophils in the sputum of adult asthmatic patients and related our findings to other parameters of eosinophilic airway inflammation.

机译：背景：嗜碱性粒细胞对哮喘发病机构的影响仍然很大程度上是未探索的，特别是在人类中。在这里，我们评估了成人哮喘患者痰中嗜碱性粒细胞的频率和激活状态，并将我们的研究结果与嗜酸性气道炎症的其他参数相关。

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来源
《Allergy》 |2017年第10期|共8页
作者
Suzuki Y.; Wakahara K.; Nishio T.; Ito S.; Hasegawa Y.;
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作者单位

Nagoya Univ Grad Sch Med Dept Resp Med Nagoya Aichi Japan;

Nagoya Univ Grad Sch Med Dept Resp Med Nagoya Aichi Japan;

Nagoya Univ Grad Sch Med Dept Resp Med Nagoya Aichi Japan;

Nagoya Univ Grad Sch Med Dept Resp Med Nagoya Aichi Japan;

Nagoya Univ Grad Sch Med Dept Resp Med Nagoya Aichi Japan;

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原文格式 PDF
正文语种 eng
中图分类医学免疫学;
关键词
basophils; biomarker; eosinophilic asthma; sputum;

机译：嗜碱性粒细胞;生物标志物;嗜酸性哮喘;痰;

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专利

1. Airway basophils are increased and activated in eosinophilic asthma [J] . Suzuki Y., Wakahara K., Nishio T., Allergy . 2017,第10期

机译：气道嗜碱性粒细胞在嗜酸性胃肠中增加和激活
2. Usefulness of basophil activation test in diagnosis of occupational nonasthmatic eosinophilic bronchitis. [J] . Pala G, Pignatti P, Perfetti L, Allergy . 2010,第7期

机译：嗜碱性粒细胞活化试验在职业性非哮喘性嗜酸性支气管炎诊断中的作用。
3. Airway platelet activation is associated with airway eosinophilic inflammation in asthma. [J] . Benton AS, Kumar N, Lerner J, Journal of investigative medicine . 2010,第8期

机译：气道血小板活化与哮喘中的气道嗜酸性炎症有关。
4. Enhancement of Antigen-Induced Eosinophilic Inflammation in the Airways of Mice by Urban Particles in Beijing [C] . Miao He, Takamichi Ichinose, Seiichi Yoshida, Conference on Environmental Pollution and Public Health . 2012

机译：北京城市颗粒增强抗原诱导的小鼠气道嗜酸性粒细胞炎症
5. A mechanism of basophil accumlation in the airways of asthmatics during natural airway narrowing: increased level of basophil chemotactic activity [D] . 丸山修寛 1992

机译：哮喘患者气道在自然气道狭窄期间嗜碱性粒细胞积累的机制：嗜碱性粒细胞趋化活性水平升高
6. Airway Platelet Activation is Associated with Airway Eosinophilic Inflammation in Asthma [O] . Angela S Benton, Nikila Kumar, Jennifer Lerner, -1

机译：气道血小板活化与哮喘中的气道嗜酸性炎症有关
7. Airway Basophils Are Activated and Associated with Eosinophilic Inflammation in Asthmatic Patients [O] . Yoshihiro Suzuki, Keiko Wakahara, Tomoko Nishio, 2016

机译：在哮喘患者中激活呼吸道嗜碱性粒细胞和与嗜酸性炎症相关的嗜酸性炎症

Airway basophils are increased and activated in eosinophilic asthma

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