Prospective evaluation of the diagnostic value of sensitive KIT D816V mutation analysis of blood in adults with suspected systemic mastocytosis

Kristensen T.; Vestergaard H.; Bindslev-Jensen C.; Mortz C. G.; Kjaer H. F.; Ollert M.; Moller M. B.; Broesby-Olsen S.

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Prospective evaluation of the diagnostic value of sensitive KIT D816V mutation analysis of blood in adults with suspected systemic mastocytosis

机译：涉嫌全身性乳细胞症血液血液血液敏感试剂盒D816V突变分析的前瞻性评价

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BackgroundSensitive KIT D816V mutation analysis of blood has been proposed to guide bone marrow (BM) investigation in suspected systemic mastocytosis (SM). The aim of this prospective study was for the first time to compare the D816V status of the screening blood sample used to guide BM biopsy in suspected SM to the outcome of the subsequent BM investigation.

机译：背景敏感试剂盒D816V血液的突变分析已经提出引导骨髓（BM）调查在疑似全身乳细胞诱导（SM）中。这项前瞻性研究的目的是第一次比较筛查血液样本的D816V状态用于指导疑似SM中的BM活组织检查到随后的BM调查的结果。

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来源
《Allergy》 |2017年第11期|共7页
作者
Kristensen T.; Vestergaard H.; Bindslev-Jensen C.; Mortz C. G.; Kjaer H. F.; Ollert M.; Moller M. B.; Broesby-Olsen S.;
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作者单位

Odense Univ Hosp Dept Pathol Odense Denmark;

Odense Univ Hosp Dept Hematol Odense Denmark;

Odense Univ Hosp Dept Dermatol Odense Denmark;

Odense Univ Hosp Dept Dermatol Odense Denmark;

Odense Univ Hosp Dept Dermatol Odense Denmark;

Odense Univ Hosp ORCA Odense Denmark;

Odense Univ Hosp Dept Pathol Odense Denmark;

Odense Univ Hosp Dept Dermatol Odense Denmark;

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原文格式 PDF
正文语种 eng
中图分类医学免疫学;
关键词
anaphylaxis; insect venom allergy; KIT D816V mutation; systemic mastocytosis; urticaria pigmentosa;

机译：过敏反应;昆虫毒液过敏;套件D816V突变;全身性乳细胞症;荨麻疹Pigmentosa;

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专利

1. Prospective evaluation of the diagnostic value of sensitive KIT D816V mutation analysis of blood in adults with suspected systemic mastocytosis [J] . Kristensen T., Vestergaard H., Bindslev-Jensen C., Allergy . 2017,第11期

机译：涉嫌全身性乳细胞症血液血液血液敏感试剂盒D816V突变分析的前瞻性评价
2. KIT D816V mutation detection: A comparative study using peripheral blood, bone marrow aspirate and bone marrow trephine samples for detection of KIT mutations in patients with systemic mastocytosis [J] . AgarwalR., McBeanM., HewittC., Leukemia and lymphoma . 2014,第9期

机译：KIT D816V突变检测：使用外周血，骨髓穿刺液和骨髓曲汀样品检测系统性肥大细胞增多症患者KIT突变的比较研究
3. Detection of the KIT D816V mutation in peripheral blood of systemic mastocytosis: diagnostic implications [J] . Maria Jara-Acevedo, Cristina Teodosio, Laura Sanchez-Mu?oz, Modern Pathology . 2015,第8期

机译：系统性肥大细胞增多症外周血 KIT D816V突变的检测：诊断意义
4. Prospective Association of DDT and DDE Exposure with High Blood Pressure among Adult Women from Mexico [C] . Martha G. Tello-Juarez, Efrain A. Terrazas-Medina, Mauricio Hernandez-Avila, Joint annual meeting of the International Society of Exposure Science and the International Society for Environmental Epidemiology . 2018

机译：墨西哥成年女性中DDT和DDE暴露与高血压的前瞻性关联
5. Air pollution source apportionment before, during, and after the 2008 Beijing Olympics and association of sources to aldehydes and biomarkers of blood coagulation, pulmonary and systemic inflammation, and oxidative stress in healthy young adults. [D] . Altemose, Brent A. 2014

机译：2008年北京奥运会之前，之中和之后的空气污染源分配，以及健康年轻人中醛类和血液凝固，肺部和系统性炎症以及氧化应激的生物标志物的来源与空气污染的关系。
6. Single-cell analysis reveals the KIT D816V mutation in haematopoietic stem and progenitor cells in systemic mastocytosis [O] . Jennine Grootens, Johanna S. Ungerstedt, Maria Ekoff, 2019

机译：单细胞分析显示系统性肥大细胞增多症造血干细胞和祖细胞中的KIT D816V突变
7. Sensitive KIT D816V mutation analysis of blood as a diagnostic test in mastocytosis [O] . Kielsgaard Kristensen Thomas, Vestergaard Hanne, Bindslev-Jensen Carsten, 2014

机译：血液敏感KIT D816V突变分析作为肥大细胞增多症的诊断测试

Prospective evaluation of the diagnostic value of sensitive KIT D816V mutation analysis of blood in adults with suspected systemic mastocytosis

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