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Calcium Supplements and Cardiovascular Disease: A Review

机译:钙补充剂和心血管疾病:综述

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Dietary or supplemental calcium intake has long been encouraged for optimal bone health. However, more recently, the safety of calcium supplementation has been questioned because of a possible association between supplemental calcium and cardiovascular risk. Whereas calcium may have a beneficial or neutral effect on cardiovascular risk factors such as blood pressure, cholesterol, weight, and diabetes, available evidence does not provide a definitive answer for an association with cardiovascular disease (CVD). To date, no calcium trials have studied cardiovascular disease as a primary end point, and larger trials with longer follow-up are needed. In this review, we present results from observational studies and randomized controlled trials (RCTs) that have evaluated calcium intake (dietary or supplemental) in relation to cardiovascular risk factors and cardiovascular disease as a secondary outcome.
机译:最佳骨骼健康长期以来一直鼓励膳食或补充钙摄入量。 然而,最近,由于补充钙和心血管风险之间的可能关联,钙补充剂的安全性已经受到质疑。 然而,钙可能对心血管危险因素(如血压,胆固醇,重量和糖尿病)具有有益或中性的影响,可用证据不提供与心血管疾病联系(CVD)的明确答案。 迄今为止,没有研究心血管疾病作为主要终点的钙试验,并且需要更大的试验更长的随访。 在本次综述中,我们呈现出从观察性研究和随机对照试验(RCT)的结果,该试验(RCTS)与心血管危险因素和心血管疾病相关评估钙摄入量(膳食或补充)作为次要结果。

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