Triblock-Diblock Composite Nanoassemblies with Sequentially Addressable Host-Guest Properties for Hydrophobics and Hydrophilics

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Triblock-Diblock Composite Nanoassemblies with Sequentially Addressable Host-Guest Properties for Hydrophobics and Hydrophilics

机译：Triblock-diblock复合纳米配件，具有依次寻址的疏水性和亲水性的主机客房

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Noncovalent encapsulation of multiple guest molecules with distinct physiochemical properties, especially hydrophilic and hydrophobic guests, into a single polymeric nanoassembly is challenging, but would be profoundly beneficial to combine with therapeutic delivery strategies. Here, we report a nanocomposite coassembled by coating a layer of an amphiphilic block copolymer onto the surface of a cross-linked inverse micelle driven by hydrophobic interactions. The hydrophobic coating layer and water-filled inverse micelles were utilized to encapsulate hydrophobic and hydrophilic cargos, respectively. Rationally introducing the pH and redox responsive moieties into the coating polymer and inverse micelles allows to sequentially address the triggered release of the encapsulated cargos.

机译：具有不同的物理化学性质，尤其是亲水和疏水性的多种客体分子的非共价封装，进入单个聚合物纳米组织是挑战性的，但与治疗交付策略结合的深刻是有益的。这里，我们通过涂覆由疏水相互作用驱动的交联的逆胶束的表面上的两亲嵌段共聚物层涂覆一层通过涂覆两亲嵌段共聚物的纳米复合材料。利用疏水涂层和水填充的逆胶束分别包封疏水性和亲水性尸体。理性地将pH和氧化还原响应部分引入涂料聚合物和逆胶束中允许顺序地解决封装的尸体的触发释放。

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《ACS Macro Letters》 |2020年第7期|共5页
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1. Triblock-Diblock Composite Nanoassemblies with Sequentially Addressable Host-Guest Properties for Hydrophobics and Hydrophilics [J] . ACS Macro Letters . 2020,第7期

机译：Triblock-diblock复合纳米配件，具有依次寻址的疏水性和亲水性的主机客房
2. Effect of hydrophilic-hydrophobic ratio in self-emulsifying amphiphilic epoxy sizing agent on interfacial properties of carbon fibre/epoxy composites [J] . Yao Jiawei, Fang Quantao, Zhang Guoliang, Progress in Organic Coatings: An International Review Journal . 2020,第1期

机译：亲水 - 疏水比在自乳化两亲环氧阳性上的影响碳纤维/环氧复合材料界面性质
3. Structure and Multifunctional Properties of the Nanocomposites Containing the hydrophilic and Hydrophobic Active Components on the Porous Polyethylene Films [J] . G. K. Elyashevich, E. Yu. Rosova, I. S. Kuryndin, Smart nanocomposites . 2014,第1期

机译：多孔聚乙烯膜上含有亲水和疏水活性成分的纳米复合材料的结构和多功能性能
4. Composites Containing Inorganic Ion Exchangers and Graphene Oxide: Hydrophilic-Hydrophobic and Sorption Properties (Review) [C] . Yuliya S. Dzyazko, Yurii M. Volfkovich, Mary O. Chaban International Conference Nanotechnology and Nanomaterials . 2021

机译：含有无机离子交换剂和石墨烯氧化物的复合材料：亲水性 - 疏水和吸附特性（审查）
5. I. Addressing the regioselectivity problem in organic synthesis. II. A-B-A-B-A block amphiphiles. Balance between hydrophilic and hydrophobic segmentation. [D] . Lu, Hao. 2009

机译：I.解决有机合成中的区域选择性问题。二。 A-B-A-B-A封闭两亲物。亲水和疏水分段之间的平衡。
6. Construction of Chiral Nanoassemblies Based on Host-Guest Complexes and Their Responsive CD and CPL Properties: Chirality Transfer From 2,6-helic[6]arenes to a Stilbazolium Derivative [O] . Yan Guo, Ying Han, Chuan-Feng Chen 1970

机译：基于宿主-客体复合物及其响应性CD和CPL性质的手性纳米组装体的构建：手性从2,6-螺旋[6]芳烃向Stilbazolium衍生物的手性转移
7. TriblockDiblock Composite Nanoassemblies with Sequentially Addressable HostGuest Properties for Hydrophobics and Hydrophilics [O] . -1

机译：TriblockDiblock复合纳米配件，具有依次寻址的HostGuest用于疏水性和亲水的主机特性

Triblock-Diblock Composite Nanoassemblies with Sequentially Addressable Host-Guest Properties for Hydrophobics and Hydrophilics

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