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首页> 外文期刊>Acta neurologica Scandinavica. >Incidence of the urological tumours in patients suffering from multiple sclerosis
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Incidence of the urological tumours in patients suffering from multiple sclerosis

机译：多发性硬化症患者泌尿外科肿瘤的发病率

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Objectives: The goal of this study was to evaluate the incidence of urological malignancies in MS patients using active screening. Material and Methods: A total of 495 MS patients (141 men, 354 women, age of 42 ± 13.4) were included in the study. The duration of disease was 12.3 ± 11 years, and the EDSS score was 4.3 (±2.5). Patients, regardless of specific urological symptoms, were referred for urological evaluation. The outcomes of these evaluations were compared with data from the 2009 National Oncology Register of the Czech Republic. Results: The standardized incidence ratio (SIR) for the whole MS study population was 38.8 (95% CI 12.6-90.6). This incidence of urological malignancies in the MS study population was higher (statistically significant) than that of the general population. The SIR for females was 66.0 (95% CI 18.0-169.1) in the MS study population, representing a statistically significant increase over that of the general female population. The increase in incidence of urological malignancies in men with MS did not reach statistical significance over that of the general male population (SIR 14.7, 95% CI 0.4-81.7). Conclusions: The incidence of urological cancer in MS patients as determined by active screening is significantly higher than that found in general population.
机译：目的：本研究的目的是通过主动筛查评估MS患者泌尿系统恶性肿瘤的发生率。材料和方法：总共495名MS患者（141名男性，354名女性，年龄42±13.4）被纳入研究。疾病持续时间为12.3±11年，EDSS评分为4.3（±2.5）。不管具体的泌尿科症状如何，都将患者转诊进行泌尿科评估。将这些评估的结果与捷克共和国2009年国家肿瘤学注册数据进行了比较。结果：整个MS研究人群的标准发生率（SIR）为38.8（95％CI 12.6-90.6）。 MS研究人群中泌尿系统恶性肿瘤的发生率高于一般人群（统计学意义）。在MS研究人群中，女性的SIR为66.0（95％CI 18.0-169.1），与一般女性人群相比，具有统计学上的显着提高。多发性硬化症男性泌尿系统恶性肿瘤发病率的增加与普通男性相比没有统计学意义（SIR 14.7，95％CI 0.4-81.7）。结论：通过主动筛查确定的MS患者泌尿外科癌症的发生率显着高于一般人群。

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