...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Current topics in microbiology and immunology >Flagellar Regulation and Virulence in the Entomopathogenic Bacteria—Xenorhabdus nematophila and Photorhabdus luminescens
【24h】

Flagellar Regulation and Virulence in the Entomopathogenic Bacteria—Xenorhabdus nematophila and Photorhabdus luminescens

机译：昆虫疗法细菌 - Xenorhabdus nematophila和Photorhabdus Luminescens的鞭毛调节和毒力

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

There is a complex interplay between the regulation of flagellar motility and the expression of virulence factors in many bacterial pathogens. Here, we review the literature on the direct and indirect roles of flagellar motility in mediating the tripartite interaction between entomopathogenic bacteria (Photorhabdus and Xenorhabdus), their nematode hosts, and their insect targets. First, we describe the swimming and swarming motility of insect pathogenic bacteria and its impact on insect colonization. Then, we describe the coupling between the expression of flagellar and virulence genes and the dynamic of expression of the flagellar regulon during invertebrate infection. We show that the flagellar type 3 secretion system (T3SS) is also an export apparatus for virulence proteins in X. nematophila. Finally, we demonstrate that phenotypic variation, a common property of the bacterial symbionts of nematodes, also alters flagellar motility in Photorhabdus and Xenorhabdus. Finally, the so-called phenotypic heterogeneity phenomenon in the flagellar gene expression network will be also discussed. As the main molecular studies were performed in X, nematophila, future perspectives for the study of the interplay between flagellum and invertebrate interactions in Photorhabdus will be discussed.
机译：在鞭毛运动的调节与许多细菌病原体中的毒力因子的表达之间存在复杂的相互作用。在这里，我们审查了鞭毛运动术中的直接和间接作用在介导昆虫致病细菌（Photorhabdus和Xenorhabdus），其线虫宿主及其昆虫靶之间的三方相互作用中的直接和间接角色。首先，我们描述了昆虫致病细菌的游泳和蜂拥而至其对昆虫定植的影响。然后，我们描述了鞭毛和毒力基因的表达与无脊椎动物感染期间鞭毛调节件的动态的偶联。我们表明，鞭毛型3分泌系统（T3SS）也是X.Nematophila毒力蛋白的出口装置。最后，我们证明了Nematodes细菌共生的一种常见性的表型变异，也改变了光炎腔和Xenorhabdus的鞭毛运动。最后，还讨论了鞭毛基因表达网络中所谓的表型异质性现象。随着主要分子研究在X，NemaTophila中进行，将讨论对鞭毛和无脊椎动物相互作用的研究的未来视角，将来将在光膜上的相互作用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号