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Appropriate analysis and presentation of data is a must for good clinical practice.

机译:良好的临床实践必须对数据进行适当的分析和呈现。

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摘要

Good Clinical Practice (GCP) is defined as an international ethical and scientific quality standard for designing, conducting, monitoring, auditing, analyzing and reporting trials that involve the participation of human subjects. This paper focuses mainly on the issues that need attention at the time of statistical analysis and reporting of results. Findings from a review of published articles in Turkey are also presented. The types of variables, the distributions of variables, the number of groups compared, the dependency structure among these groups and the primary goal of the analysis determine the appropriate method to be selected for the statistical analysis. The review of a stratified sample of research articles from 60 journals published in 1992 in Turkey revealed that in 56% of the cases the statistical methods were improper or inadequate. In 15% of the articles the authors failed to select an appropriate design for the proposed aim mentioned in the manuscript. Despite the recent improvements, the necessity and the value of performing and presenting research according to the international standards remains to be assimilated better by Turkish investigators.
机译:良好临床规范(GCP)被定义为一项国际道德和科学质量标准,用于设计,进行,监测,审计,分析和报告涉及人类受试者参与的试验。本文主要关注统计分析和结果报告时需要注意的问题。还介绍了对土耳其已发表文章的评论发现的结果。变量的类型,变量的分布,比较的组数,这些组之间的依存关系以及分析的主要目标决定了要为统计分析选择的适当方法。对1992年在土耳其出版的60种期刊的分层研究样本样本的审查显示,在56%的案例中,统计方法不正确或不适当。在15%的文章中,作者未能为手稿中提到的拟议目标选择合适的设计。尽管最近有了改进,但根据土耳其的调查人员仍需更好地吸收按照国际标准进行和展示研究的必要性和价值。

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