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首页> 外文期刊>American journal of industrial medicine >Impulse oscillometry measurement of distal airways obstruction in depleted uranium‐exposed Gulf War veterans
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Impulse oscillometry measurement of distal airways obstruction in depleted uranium‐exposed Gulf War veterans

机译：耗尽铀暴露海湾战争退伍军人远端气道阻塞的脉冲示波器测量

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Introduction A cohort of Gulf War I veterans who sustained exposure to depleted uranium undergoes biennial surveillance for potential uranium‐related health effects. We performed impulse oscillometry and hypothesized that veterans with higher uranium body burdens would have more obstructive abnormalities than those with lower burdens. Methods We compared pulmonary function of veterans in high versus low urine uranium groups by evaluating spirometry and oscillometry values. Results Overall mean spirometry and oscillometry resistance values fell within the normal ranges. There were no significant differences between the high and low uranium groups for any parameters. However, more veterans were classified as having obstruction by oscillometry (42%) than spirometry (8%). Conclusions While oscillometry identified more veterans as obstructed, obstruction was not uranium‐related. However, the added sensitivity of this method implies a benefit in wider surveillance of exposed cohorts and holds promise in identifying abnormalities in areas of the lung historically described as silent.
机译：引进海湾战争队伍的退伍军人持续暴露在耗尽铀的退伍军人进行两年期监测，用于潜在的铀相关的健康影响。我们进行了脉冲示波器，并假设具有较高铀体重的退伍军人比具有较低负担的人具有更大的阻塞性异常。方法通过评价血液计量和示波器值对高尿铀基团的肺功能与高尿铀组进行比较。结果总体平均肺活量和振动性抗性值在正常范围内下降。对于任何参数，高铀群之间没有显着差异。然而，更多的退伍军人被归类为通过示波器（42％）的阻塞而不是肺活量测定法（8％）。结论虽然示波器确定了更多退伍军人被阻塞，但梗阻不是铀相关性。然而，该方法的增加的敏感性意味着更广泛监视暴露的群组的益处，并持有历史描述为沉默的肺部区域的异常。

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