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首页> 外文期刊>Anesthesia and Analgesia: Journal of the International Anesthesia Research Society >A comparison of 3% hypertonic saline and mannitol for brain relaxation during elective supratentorial brain tumor surgery.
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A comparison of 3% hypertonic saline and mannitol for brain relaxation during elective supratentorial brain tumor surgery.

机译：选修脑肿瘤手术中3％高渗盐水和甘露醇对脑松弛的比较。

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BACKGROUND: In this study, we compared the effects of 3% hypertonic saline (HTS) and 20% mannitol on brain relaxation during supratentorial brain tumor surgery, intensive care unit (ICU) stays, and hospital days. METHODS: This prospective, randomized, and double-blind study included patients who were selected for elective craniotomy for supratentorial brain tumors. Patients received either 160 mL of 3% HTS (HTS group, n = 122) or 150 mL of 20% mannitol infusion (M group, n = 116) for 5 minutes at the start of scalp incision. The PCO(2) in arterial blood was maintained within 35 to 40 mm Hg, arterial blood pressure was controlled within baseline values +/-20%, and positive fluid balance was maintained intraoperatively at a rate of 2 mL/kg/h. Outcome measures included fluid input, urine output, arterial blood gases, serum sodium concentration, ICU stays, and hospital days. Surgeons assessed the condition of the brain as "tight,
机译：背景：在这项研究中，我们将3％高渗盐水（HTS）和20％甘露醇对脑放松的影响进行了比较了在SuprateLential脑肿瘤外科，重症监护室（ICU）住宿和医院时期。 方法：这种前瞻性，随机和双盲研究包括为Suprateential脑肿瘤选择选择性的Craniotomy患者。 在头皮切口开始时，患者接受160mL 3％HTS（HTS基团，N = 122）或150ml 20％甘露醇输注（M组，N = 116）。 动脉血液中的PCO（2）保持在35至40mm Hg内，在基线值+/-20％内控制动脉血压，并以2mL / kg / h的速率保持正液平衡。 结果措施包括流体输入，尿产输出，动脉血液，血清钠浓度，ICU住宿和医院日。 外科医生评估大脑的状况为“紧张”，

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