F-18-florbetapir Positron Emission Tomography-determined Cerebral -Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery

Klinger Rebecca Y.; James Olga G.; Borges-Neto Salvador; Bisanar Tiffany; Li Yi-Ju; Qi Wenjing; Berger Miles; Terrando Niccolo; Newman Mark F.; Doraiswamy P. Murali; Mathew Joseph P.

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F-18-florbetapir Positron Emission Tomography-determined Cerebral -Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery

机译：F-18 - 浮动血管正电子发射断层扫描确定的脑 - 锯形沉积和心脏手术后神经认知性能

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Background: Amyloid deposition is a potential contributor to postoperative cognitive dysfunction. The authors hypothesized that 6-week global cortical amyloid burden, determined by F-18-florbetapir positron emission tomography, would be greater in those patients manifesting cognitive dysfunction at 6 weeks postoperatively.

机译：背景：淀粉样蛋白沉积是潜在的潜在贡献者对术后认知功能障碍。假设由F-18-Florbetapir Corrdron排放断层扫描确定的6周全球皮质淀粉样蛋白负担，在术后6周，在术后6周患者将更大。

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《Anesthesiology》 |2018年第4期|共17页
作者
Klinger Rebecca Y.; James Olga G.; Borges-Neto Salvador; Bisanar Tiffany; Li Yi-Ju; Qi Wenjing; Berger Miles; Terrando Niccolo; Newman Mark F.; Doraiswamy P. Murali; Mathew Joseph P.;
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作者单位

Duke Univ Dept Anesthesiol Box 3094 2301 Erwin Rd Durham NC 27710 USA;

Duke Univ Dept Radiol Durham NC 27710 USA;

Duke Univ Dept Radiol Durham NC 27710 USA;

Duke Univ Dept Anesthesiol Box 3094 2301 Erwin Rd Durham NC 27710 USA;

Duke Univ Dept Biostat &

Bioinformat Durham NC USA;

Duke Univ Dept Biostat &

Bioinformat Durham NC USA;

Duke Univ Dept Anesthesiol Box 3094 2301 Erwin Rd Durham NC 27710 USA;

Duke Univ Dept Anesthesiol Box 3094 2301 Erwin Rd Durham NC 27710 USA;

Duke Univ Dept Anesthesiol Box 3094 2301 Erwin Rd Durham NC 27710 USA;

Duke Univ Dept Psychiat &

Behav Sci Durham NC USA;

Duke Univ Dept Anesthesiol Box 3094 2301 Erwin Rd Durham NC 27710 USA;

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正文语种 eng
中图分类麻醉学;
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1. F-18-florbetapir Positron Emission Tomography-determined Cerebral -Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery [J] . Klinger Rebecca Y., James Olga G., Borges-Neto Salvador, Anesthesiology . 2018,第4期

机译：F-18 - 浮动血管正电子发射断层扫描确定的脑 - 锯形沉积和心脏手术后神经认知性能
2. Association between Cerebral Amyloid Deposition and Clinical Factors Including Cognitive Function in Geriatric Depression: Pilot Study Using Amyloid Positron Emission Tomography [J] . Hye-Geum Kim, Eun-Jung Kong, Eun-Jin Cheon, Clinical Psychopharmacology and Neuroscience . 2016,第4期

机译：脑淀粉样蛋白沉积与老年抑郁症中包括认知功能在内的临床因素之间的关联：使用淀粉样蛋白正电子发射断层扫描的先导研究
3. Reduction in amyloid β deposition on 18 F-florbetapir positron emission tomography with correction of cerebral hypoperfusion after endarterectomy for carotid stenosis [J] . Kuniaki Ogasawara, Shunrou Fujiwara, Kohei Chida, American Journal of Nuclear Medicine and Molecular Imaging . 2019,第6期

机译：减少18 F - 荧光β沉积的淀粉样蛋白β沉积与颈动脉狭窄后颞下颌切除术后脑低渗
4. Positron emission tomography radioligands for neuroimaging of βamyloid [C] . Samuel P.S. Svensson, Britt-Marie Swahn, Anders Juréus, Annual meeting exposition of the Controlled Release Society . 2009

机译：正电子发射断层扫描放射配体对β淀粉样蛋白的神经成像
5. Inflammation dependent cerebral deposition of serum amyloid A proteins in amyloid mouse model. [D] . Guo, Jun-tao. 2001

机译：炎症依赖的淀粉样蛋白小鼠模型中血清淀粉样蛋白A蛋白的脑沉积。
6. 18F-florbetapir PET-determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery [O] . Rebecca Y. Klinger, Olga G. James, Salvador Borges-Neto, -1

机译：18F-florbetapir PET决定的心脏手术后脑β-淀粉样蛋白沉积和神经认知功能
7. 18F-florbetapir Positron Emission Tomography–determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery [O] . Rebecca Y. Klinger, Olga G. James, Salvador Borges-Neto, 2018

机译：18F-Florbetapir正电子发射断层扫描确定的脑β-淀粉样蛋白沉积和心脏手术后神经认知性能

F-18-florbetapir Positron Emission Tomography-determined Cerebral -Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery

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