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Precuneus proportions and cortical folding: A morphometric evaluation on a racially diverse human sample

机译:priaveus比例和皮质折叠:在种族多样化的人类样本上的形态学评估

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Recent analyses have suggested that the size and proportions of the precuneus are remarkably variable among adult humans, representing a major source of geometrical difference in midsagittal brain morphology. The same area also represents the main midsagittal brain difference between humans and chimpanzees, being more expanded in our species. Enlargement of the upper parietal surface is a specific feature of Homo sapiens, when compared with other fossil hominids, suggesting the involvement of these cortical areas in recent modern human evolution. Here, we provide a survey on midsagittal brain morphology by investigating whether precuneus size represents the largest component of variance within a larger and racially diverse sample of 265 adult humans. Additionally, we investigate the relationship between precuneus shape variation and folding patterns. Precuneus proportions are confirmed to be a major source of human brain variation even when racial variability is considered. Larger precuneus size is associated with additional precuneal gyri, generally in its anterior district. Spatial variation is most pronounced in the dorsal areas, with no apparent differences between hemispheres, between sexes, or among different racial groups. These dorsal areas integrate somatic and visual information together with the lateral elements of the parietal cortex, representing a crucial node for self-centered mental imagery. The histological basis and functional significance of this intra-specific variation in the upper precuneus remains to be evaluated. (C) 2017 Elsevier GmbH. All rights reserved.
机译:最近的分析表明,预测的大小和比例在成人人类中具有显着变化,代表了中间显性脑形态的几何差异来源。同一区域还代表了人类和黑猩猩之间的主要脑卒中脑差异,在我们的物种中更加扩展。与其他化石同源物相比,上间表面的扩大是HOMO SAPIENS的一种特征,表明这些皮质区域在近期现代人类演变中的参与。在这里,我们通过调查前雄尺寸是否代表了265名成年人的265个成年人样本中的最大方差分量的最大方差组分的调查。此外,我们研究了前像形状变化和折叠模式之间的关系。即使考虑种族变异性,也确认了预测的前源是人脑变化的主要来源。较大的预防静脉大小与额外的PrecuinealGyri相关联,通常在其前区。背部区域最明显的空间变异,半球之间没有明显差异,性别之间或不同种族群之间。这些背部区域与顶部皮质的侧部元素一起将体细胞和视觉信息集成在一起,代表了自我中心精神图像的关键节点。上下前守前的这种特异性变化的组织学基础和功能性意义仍有待评估。 (c)2017 Elsevier GmbH。版权所有。

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