首页> 外文期刊>Annals of anatomy =: Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft >Endoneurial-CD34 positive cells define an intermediate layer in human digital Pacinian corpuscles
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Endoneurial-CD34 positive cells define an intermediate layer in human digital Pacinian corpuscles

机译:内部脉冲CD34阳性细胞在人数字伏西纳群中定义中间层

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The endoneurial and/or perineurial origin of the outer core; i.e. the concentric and continuous lamellae located outside the complex formed by the axon and the Schwann-related cells, in human Pacinian corpuscles is still debated. Here we used immunohistochemistry coupled with a battery of antibodies to investigate the expression of perineurial (Glucose transporter 1 and epithelial membrane antigen) or endoneurial (CD34 antigen) markers in human digital Pacinian corpuscles. CD34 immunoreactivity was restricted to one layer immediately outside the inner core, whereas the proper outer core displayed antigens typical of the perineurial cells. These results demonstrate an intermediate endoneurial layer that divides the Pacinian corpuscles into two distinct compartments: the avascular inner neural compartment (formed by the axon and the Schwann-related cells that form the inner core), and the outer non-neural compartment (formed by the outer core). The functional relevance of these findings, if any, remains to be clarified. (C) 2017 Elsevier GmbH. All rights reserved.
机译:外核的内部和/或突出源;即,位于轴突和施旺相关细胞形成的复合物外的同心和连续薄片仍然讨论。在这里,我们使用免疫组织化学与抗体的电池耦合,以研究人体数字式伏替氏植物中的脑膜炎(葡萄糖转运蛋白1和上皮膜抗原)或内腔(CD34抗原)标志物的表达。 CD34免疫反应性限制在内芯外立即的一层,而适当的外核显示出典型的阴部细胞的抗原。这些结果证明了一种中间内腔层,其将伏氏藻氏菌分成两个不同的隔室:储备内部神经隔室(由轴突形成和形成内核的施旺相关细胞),以及外部非神经隔室(由)外核)。这些发现的功能相关性,如果有的话,仍有待澄清。 (c)2017 Elsevier GmbH。版权所有。

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