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首页> 外文期刊>BJOG: an international journal of obstetrics and gynaecology >Laterality in five-year-olds conceived by intracytoplasmic sperm injection, standard in vitro fertilisation and natural conception: a European study.
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Laterality in five-year-olds conceived by intracytoplasmic sperm injection, standard in vitro fertilisation and natural conception: a European study.

机译：欧洲一项研究，通过胞浆内精子注射，标准体外受精和自然受孕受孕的五岁儿童的侧身性。

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摘要

Objective To assess laterality in a group of European children conceived with the help of assisted reproductive therapy, or naturally conceived. Design Prospective cohort study. Setting Five European countries. Population A total of 1525 five-year-old children divided into three groups according to conception status: naturally conceived; intracytoplasmic sperm injection (ICSI); in vitro fertilisation (IVF) group. Methods All children were assessed using the McCarthy Scale of Children's Abilities (Motor Scale) with additional items using a comb, a spoon and an indirect measure was made of the parental handedness scores, using a questionnaire. Main outcome measures Child handedness for drawing and writing. Results Observed handedness did not differ significantly between natural conception, IVF and ICSI in girls or boys, except for ICSI-conceived girls, fewer of whom were left-handed than the naturally conceived controls, 7.0%versus 12.4% (P < 0.05), however, this was close to the population norm of 8%. The degree of parental handedness did not significantly vary in the three groups. Conclusions Laterality, as assessed by handedness, may be marginally less common in girls conceived with assisted reproductive therapies than with children conceived naturally.
机译：目的评估一组在辅助生殖治疗的帮助下或自然受孕的欧洲儿童的偏侧性。设计前瞻性队列研究。设置五个欧洲国家。人口总共1525名五岁儿童根据受孕状况分为三类：自然受孕;胞浆内精子注射（ICSI）;体外受精（IVF）组。方法采用麦卡锡儿童能力量表（运动量表）对所有儿童进行评估，并用梳子，勺子对其他项目进行评估，并通过问卷调查间接测量父母的亲手性得分。主要结果指标儿童绘画和书写的惯用性。结果男孩或男孩的自然受孕，IVF和ICSI的观察到的惯性没有显着差异，除了ICSI受孕的女孩，左撇子的人数少于自然受孕的对照组，分别为7.0％和12.4％（P <0.05），但是，这接近8％的人口标准。三组中父母的亲和力程度没有显着差异。结论按惯用手法评估，受助生殖疗法的女孩的侧身性可能比自然受孕的儿童略少。

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