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首页> 外文期刊>Annals of epidemiology >Interpregnancy weight change and adverse maternal outcomes: a?retrospective cohort study
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Interpregnancy weight change and adverse maternal outcomes: a?retrospective cohort study

机译:令人敬畏的体重变化和不利的产妇结果:a?回顾性队列研究

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Abstract Purpose Examine associations between interpregnancy body mass index (BMI) change (difference in the pre-pregnancy BMIs of two consecutive pregnancies) and gestational diabetes mellitus (GDM), pre-eclampsia (PE), gestational hypertension (GHtn), primary cesarean delivery, and vaginal birth after cesarean delivery (VBAC). Methods Modified Poisson regression models estimated adjusted associations. Results Every 1-unit increase in interpregnancy BMI increased risks of GDM (relative risk [RR]: 1.09; 95% confidence interval [CI], 1.07–1.11), PE (RR: 1.06; 95% CI, 1.04–1.09), GHtn (RR: 1.08; 95% CI, 1.06–1.10), and primary cesarean delivery (RR: 1.03; 95% CI, 1.01–1.05) and decreased the risk of a successful VBAC (RR: 0.98; 95% CI: 0.97–0.997) in the second pregnancy. A BMI increase of ≥3 units increased risks of GDM (RR: 1.71, 95% CI, 1.52–1.93), PE (RR: 1.60, 95% CI, 1.33–1.94), GHtn (RR: 1.66, 95% CI, 1.42–1.94), and primary cesarean delivery (RR: 1.29, 95% CI, 1.12–1.49) and decreased the risk of a successful VBAC (RR: 0.89; 95% CI, 0.80–0.99) compared to women with interpregnancy BMI change within??1 and?+1 unit. GDM was also increased among women increasing their BMI by?≥2 but Conclusion An interpregnancy BMI increase of ≥3 units is associated with an increased risk of all outcomes. These findings emphasize the importance of interpregnancy weight management.
机译:摘要目的审查忧心体重指数(BMI)变化(连续怀孕前BMI的差异)和妊娠期糖尿病(GDM),预先异化糖尿病(PE),妊娠期高血压(GHTN),初级剖宫产剖宫产后的阴道分娩(VBAC)。方法修改泊松回归模型估计调整关联。结果每1单位增加诠释性BMI增加GDM的风险(相对风险[RR]:1.09; 95%置信区间[CI],1.07-1.11),PE(RR:1.06; 95%CI,1.04-1.09), GHTN(RR:1.08; 95%CI,1.06-1.10)和初级剖宫产(RR:1.03; 95%CI,1.01-1.05)并降低成功VBAC的风险(RR:0.98; 95%CI:0.97 -0.997)在第二次怀孕中。 BMI增加≥3个单位增加了GDM的风险(RR:1.71,95%CI,1.52-1.93),PE(RR:1.60,95%CI,1.33-1.94),GHTN(RR:1.66,95%CI, 1.42-1.94)和初级剖宫产(RR:1.29,95%CI,1.12-1.49)并降低成功VBAC的风险(RR:0.89; 95%CI,0.80-0.99),与具有引人注目的BMI变化的女性相比在?? 1和?+1单位内。在增加他们的BMI的女性中,GDM也增加了BMI?≥2但结论令人瞩目的BMI增加≥3个单位的增加与所有结果的风险增加有关。这些调查结果强调了侵袭性重量管理的重要性。

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