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Examining racial disparities in colon cancer clinical delay in the Colon Cancer Patterns of Care in Chicago study

机译:检查芝加哥研究中结肠癌临床延迟结肠癌的种族差异

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Abstract Purpose We explored a potential racial disparity in clinical delay among non-Hispanic (nH) Black and White colon cancer patients and examined factors that might account for the observed disparity. Methods Patients aged 30–79?years with a newly diagnosed colon cancer from 2010 to 2014 ( n ?= 386) were recruited from a diverse sample of nine public, private, and academic hospitals in and around Chicago. Prolonged clinical delay was defined as 60 days or more or 90?days or more between medical presentation (symptoms or a screen-detected lesion) and treatment initiation (surgery or chemotherapy). Multivariable logistic regression with model-based standardization was used to estimate the disparity as a difference in prevalence of prolonged delay by race. Results Prevalence of delay in excess of 60?days was 12 percentage points (95% confidence interval: 2%, 22%) higher among nH Blacks versus Whites after adjusting for age, facility, and county of residence. Travel burden (time and distance traveled from residence to facility) explained roughly one-third of the disparity (33%, P ?= .05), individual and area-level socioeconomic status measures explained roughly one-half (51%, P ?= .21), and socioeconomic measures together with travel burden explained roughly four-fifths (79%, P ?=?.08). Conclusions Low socioeconomic status and increased travel burden are barriers to care disproportionately experienced by nH Black colon cancer patients.
机译:摘要目的我们探讨了非西班牙裔(NH)黑白结肠癌患者的临床延迟的潜在种族差异,并检查了可能占观察到的差异的因素。方法患者30-79岁的患者,从2010年到2014年(n?= 386)的新诊断出的结肠癌(n?= 386)是从芝加哥及其周边及其周围地区的九个公共,私人和学院的各种样本招募。延长的临床延迟定义为60天或更长时间或90℃或更长时间或更长的医学呈现(症状或筛选病变)和治疗开始(手术或化疗)。基于模型的标准化的多变量逻辑回归用于估计差异作为竞争延长延迟普遍的差异。结果延迟超过60的延迟率为12个百分点(95%置信区间:2%,22%)在调整年龄,设施和居住县后,NH黑色与Whites相比。旅行负担(从居住地前往设施的时间和距离)解释了大约三分之一的差异(33%,P?= .05),个人和面积级社会经济地位措施大约一半(51%,P? = .21),社会经济措施与旅行负担一起解释了大约五分之五(79%,p?= 08)。结论,社会经济地位低,行程负担的增加是NH黑色结肠癌患者不成比例地经历的障碍。

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