...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>ANZ journal of surgery >Heterogeneous survival between stage IIA IIA and stage IIIA IIIA colon cancer when different numbers of lymph nodes are harvested
【24h】

Heterogeneous survival between stage IIA IIA and stage IIIA IIIA colon cancer when different numbers of lymph nodes are harvested

机译：当收获不同数量的淋巴结时，IIA型IIA和IIIa IIIA IIIA IIIa IIIa IIIA的异质存活

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background We aim to compare the prognosis between patients with stage IIA and stage IIIA colon cancer. Methods We analysed patients with stage IIA or stage IIIA colon cancer based on data from the US Surveillance, Epidemiology, and End Results ( SEER ) database. Survival data were generated as Kaplan–Meier curves and were compared by log‐rank tests. A multivariate Cox proportional hazards model was used to analyze the risk factors. Results In total, 43?379 patients (38?784 stage IIA and 4595 stage IIIA ) were included from the SEER database. A Kaplan–Meier analysis showed no significant difference between patients with stage IIA and IIIA colon cancer ( P ?=?0.547). In the subgroup of patients with number of lymph nodes harvested ( LNH ) ≥12, a multivariate analysis showed that compared with stage IIA patients, stage IIIA patients were more likely to have a poorer cancer‐specific survival ( CSS ) (hazard ratio ( HR ) 1.252, 95% confidence interval ( CI ) 1.095–1.431, P ?=?0.001). In the subgroup of patients with LNH 12, a multivariate analysis showed that compared with stage IIA patients, stage IIIA patients were more likely to have a better CSS ( HR 0.820, 95% CI 0.731–0.919, P ?=?0.001). Conclusions Patients with stage IIA colon cancer had a CSS comparable with that of patients with stage IIIA disease. When adequate lymph nodes were retrieved ( LNH ≥12), stage IIA patients had a greater CSS than stage IIIA patients. On the contrary, when inadequate lymph nodes were retrieved ( LNH 12), stage IIA patients had a poorer CSS than stage IIIA patients.
机译：背景技术我们的目标是比较IIA阶段和IIIA阶段结肠癌患者之间的预后。方法对来自美国监测，流行病学和最终结果（SEER）数据库的数据分析患有IIA阶段或IIIA阶段结肠癌的患者。生存数据被生存为Kaplan-Meier曲线，并通过记录级测试进行比较。多变量Cox比例危险模型用于分析风险因素。结果，43岁？379名患者（38岁？784阶段和4595阶段IIIA）被列入了SEER数据库。 KAPLAN-MEIER分析显示IIA期和IIIA结肠癌患者之间没有显着差异（P？= 0.547）。在收获的淋巴结数（LNH）≥12患者的亚组中，多变量分析表明，与阶段IIA患者相比，IIIA期患者更容易具有较差的癌症癌症存活（CSS）（危险比（人力资源） ）1.252,95％置信区间（CI）1.095-1.431，P？= 0.001）。在LNH＆lt中的亚组中，多变量分析表明，与阶段IIA患者相比，IIIA期患者更容易具有更好的CSS（HR 0.820,95％CI 0.731-0.919，P？= 0.001） 。结论IIA阶段结肠癌患者的CSS与IIIA期患者的CSS相当。当检索足够的淋巴结（LNH≥12）时，IIA阶段患者的CSS比IIIA阶段更大。相反，当检索不足的淋巴结（LNH 12）时，IIA阶段患者比IIIA阶段患者较差。

著录项

  • 来源
    《ANZ journal of surgery》 |2018年第4期|共6页
  • 作者

    Huang Ben; Feng Yang; Ni Mengdong; Chen Chen; Cai Guoxiang;

  • 作者单位

    Department of Colorectal SurgeryFudan University Shanghai Cancer CenterShanghai China;

    Department of Colorectal SurgeryFudan University Shanghai Cancer CenterShanghai China;

    Department of Colorectal SurgeryFudan University Shanghai Cancer CenterShanghai China;

    Department of Colorectal SurgeryFudan University Shanghai Cancer CenterShanghai China;

    Department of Colorectal SurgeryFudan University Shanghai Cancer CenterShanghai China;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 外科学;
  • 关键词

    colon cancer; lymph node; stage IIA; stage IIIA; survival;

    机译：结肠癌;淋巴结;阶段IIA;第IIIA阶段;生存;

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号