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首页> 外文期刊>ANZ journal of surgery >Total thyroidectomy for pressure symptoms in patients with H H ashimoto's thyroiditis
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Total thyroidectomy for pressure symptoms in patients with H H ashimoto's thyroiditis

机译:Hashimoto甲状腺炎患者的压力症状总甲状腺切除术

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Background Hashimoto's thyroiditis ( HT ) is rarely on its own the indication for thyroidectomy. However, surgery in patients with HT will be undertaken when there is malignancy and may be required for pressure symptoms. Therefore, this study aimed to investigate the indications for surgery in HT patients. Methods The Monash University Endocrine Surgery Database was analysed from 1994 to 2013 for patients with HT . Patients with HT were compared to a similar group of patients with no HT on histopathology. Patient demographics, indication for surgery, histopathology, gland weight and complications were analysed. Results A total of 2346 patients underwent total thyroidectomy during the study period. The median age was 55 years. Eleven percent of patients had HT on final pathology (259/2346). HT patients reported more pressure symptoms, 25.5% compared to those with other pathology, 18.9% ( P ?=?0.01). Patients with pressure symptoms had heavier glands, 113?g compared to 85?g in those with other indications for surgery ( P ?=?0.048). Within the HT cohort, the median gland weight was 66?g compared to 93?g in those without HT ( P ??0.01). On multivariate analysis, pressure symptoms as an indication for surgery was associated with HT ( P ??0.01), but age, gender and gland weight were not associated. In patients operated for pressure with HT as the only pathology, 90% had relief of pressure symptoms. Conclusion Patients with HT were more likely to have pressure symptoms as an indication for surgery independent of gland weights.
机译:背景技术Hashimoto的甲状腺炎(HT)很少在它自己的甲状腺切除术的指示。然而,HT患者的手术将在恶性肿瘤时进行,并且可能需要压力症状。因此,本研究旨在调查HT患者手术的适应症。方法为1994年至2013年分析蒙纳士大学内分泌外科数据库,用于HT患者。将HT患者与一组类似的患者进行比较,患者组织病理学没有HT。分析了患者人口统计学,分析了手术,组织病理学,腺体重量和并发症的指示。结果共有2346名患者在研究期间接受了总甲状腺切除术的患者。中位年龄为55年。 11%的患者在最终病理学上有HT(259/2346)。 HT患者报告了更多的压力症状,与其他病理学相比,25.5%,18.9%(P?= 0.01)。压力症状的患者腺体较重,113?g相比于85μg的手术中的其他适应症(p?= 0.048)。在HT队列中,中间腺体重量为66μm,而没有HT HT的93μg(p≤≤0.01)。在多变量分析中,作为手术指示的压力症状与HT(p≤≤0.01)相关,但年龄,性别和腺体重量无关。在用HT的患者下载压力的患者中,90%的压力症状缓解。结论HT的患者更有可能具有压力症状,作为独立于腺体重量的手术的指示。

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