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首页> 外文期刊>ANZ journal of surgery >Incidence of pulmonary embolism in patients with newly diagnosed colorectal cancer
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Incidence of pulmonary embolism in patients with newly diagnosed colorectal cancer

机译：新诊断结直肠癌患者肺栓塞发病率

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Background Studies have suggested a benefit from extended venous thromboprophylaxis post‐operatively in colorectal cancer with an assumed base rate of zero venous thromboembolic events prior to treatment. We aim to establish the incidence of pulmonary embolism in patients with newly diagnosed stage III or IV colorectal cancer prior to any treatment. Method Consecutive patients presenting to a single health service with a new diagnosis of stage III or IV colorectal cancer were identified from a prospective database, for the period between January 2011 and September 2014. Contemporaneous clinical data was reviewed. Included patients had a computerized tomography (CT) chest scan for pre‐operative staging for cancer. The diagnosis of pulmonary emboli was made on chest CT. Results Of 330 patients identified, 224 had baseline CT chest imaging available for review, of which 107 (47.8%) were technically adequate scans. Pulmonary emboli were identified on five (4.7%) of these 107, including one of five patients (1.7%) with stage III and four of five patients (8.3%) with stage IV disease. None of the 107 patients with adequate scans had post‐operative pulmonary emboli or deep vein thrombosis. Conclusion There is a clinically significant baseline rate of asymptomatic pulmonary emboli in patients with stage III and IV colorectal cancer that can be demonstrated on the staging chest CT scan. Pulmonary emboli described as a post‐operative event in previous series may have been present prior to surgery.
机译：背景技术在治疗前，在结肠直肠癌中，在结肠直肠癌后可操作地从延伸的静脉缩进血管基血管癌中提出了一种益处。我们的目标是在任何治疗之前建立新诊断的阶段III或IV结直肠癌患者的肺栓塞发病率。方法在2011年1月至2011年1月至2014年9月期间，从潜在数据库中确定了患有阶段III或IV结直肠癌的新诊断的单一卫生服务的患者。审查了同期临床数据。包括患者有一种电脑断层扫描（CT）胸部扫描，用于癌症预持续分期。胸部栓塞的诊断是在胸部CT上进行的。结果为330名患者，224名患者提供基线CT胸部成像，可供审查，其中107（47.8％）在技术上是充足的扫描。肺部栓子在这107中的五（4.7％）中鉴定出五（4.7％），其中5名患者中的一项（1.7％），其中第三阶段和四个患者中有四个患者（8.3％）。 107例足够扫描的107名患者中没有患病后肺部栓塞或深静脉血栓形成。结论III期和IV型结直肠癌患者的无症状肺栓塞的临床上显着的基线基线，可以在分期胸部CT扫描上证明。在手术之前可能存在作为先前系列的术后事件的肺部栓塞。

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