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首页> 外文期刊>ANZ journal of surgery >Neutrophil‐to‐lymphocyte ratio predicts anastomotic dehiscence
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Neutrophil‐to‐lymphocyte ratio predicts anastomotic dehiscence

机译：中性粒细胞到淋巴细胞比率预测吻合裂缝

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Background Anastomotic dehiscence (AD) is the most feared complication following colonic and rectal anastomosis. Multiple attempts have been made to correlate the levels of biomarkers to the risk of AD. This study attempts to compare C‐reactive protein (CRP), procalcitonin (PCT) and neutrophil‐to‐lymphocyte ratio (NLR) as predictors of AD. Method This case‐controlled study collected data on patients undergoing colonic and rectal anastomosis over an 18‐month period. Levels of CRP, PCT and NLR were recorded daily for the first 5 days post‐operatively. These results were then compared between those who developed AD and those who did not. Results A total of 136 patients were included; 11 (8.1%) patients developed AD. CRP and NLR were useful predictors of AD with an area under the curve of 0.81 and 0.78 on post‐operative day 4. PCT was not found to be raised significantly higher in patients who developed AD compared to those who did not. Conclusion CRP and NLR are useful predictors of AD. PCT is not a useful predictor of AD.
机译：背景技术吻合裂缝（AD）是结肠癌和直肠吻合术后最令人担忧的并发症。已经进行了多次尝试，将生物标志物的水平与广告的风险相关联。该研究试图将C反应蛋白（CRP），ProCalcitonin（PCT）和中性粒细胞至淋巴细胞比（NLR）与AD的预测因子进行比较。方法本病例控制的研究收集了在18个月内接受过肠癌和直肠吻合术的患者的数据。可操作后前5天每天记录CRP，PCT和NLR的水平。然后将这些结果与那些开发广告的人和那些没有的结果进行比较。结果共有136名患者; 11（8.1％）患者开发了广告。 CRP和NLR在操作后第4天的曲线下具有0.81和0.78的面积的有用预测因子。4. PCT未发现与没有的人开发广告的患者显着提高。结论CRP和NLR是广告的有用预测因子。 PCT不是广告的有用预测因素。

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