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Appetite disorders in cancer patients: Impact on nutritional status and quality of life

机译：癌症患者的食欲障碍：对营养状况和生活质量的影响

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Cancer patients are at high risk of malnutrition due to several symptoms such as lack of appetite. The aim of this study was to determine the prevalence of different appetite disorders in cancer patients and their influence on dietary intake, nutritional status, and quality of life. We conducted a cross-sectional study of cancer patients at risk of malnutrition. Nutritional status was studied using Subjective Global Assessment, anthropometry, and grip strength. Dietary intake was evaluated with a 24-h recall, and patients were questioned about the presence of changes in appetite (none, anorexia, early satiety, or both). Quality of life was measured using EORTC-QLQ-C30. Multivariate analysis was performed using linear regression. 128 patients were evaluated. 61.7% experienced changes in appetite: 31% anorexia, 13.3% early satiety, and 17.2% both. Appetite disorders were more common in women and with the presence of cachexia. The combination of anorexia and satiety resulted in a lower weight and BMI. However, there were no significant effects on energy or macronutrient intake among different appetite alterations. Patients with a combination of anorexia and early satiety had worse overall health perception, role function, and fatigue. Appetite disorders are highly prevalent among cancer patients at risk of malnutrition. They have a significant impact on nutritional status and quality of life, especially when anorexia and early satiety are combined. (C) 2017 Elsevier Ltd. All rights reserved.
机译：由于缺乏食欲的症状，癌症患者患营养不良的风险很高。本研究的目的是确定癌症患者不同食欲障碍的患病率及其对膳食摄入，营养状况和生活质量的影响。我们对营养不良风险进行了对癌症患者的横截面研究。使用主观全局评估，人类测定法和握力研究营养状况。用24小时召回评估膳食摄入量，患者对食欲的变化（无，厌食，早期饱腹感或两者）有质疑。使用EORTC-QLQ-C30测量寿命的质量。使用线性回归进行多变量分析。评估128名患者。 61.7％的食欲变化：31％厌食，早期饱腹腹筋13.3％，均为17.2％。食欲障碍在女性和患者的存在中更常见。厌食症和饱腹感的组合导致重量和BMI较低。然而，对不同食欲改变之间的能量或Macronourient摄入没有显着影响。厌食症和早期饱腹感组合的患者具有更糟糕的整体健康感知，角色功能和疲劳。食欲障碍在营养不良风险的癌症患者中普遍存在。它们对营养状况和生活质量产生重大影响，特别是当厌食和早期饱腹感组合时。 （c）2017 Elsevier Ltd.保留所有权利。

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