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首页> 外文期刊>Aquaculture International >The efficacy of Streptococcus agalactiae vaccine preparations, administered to tilapia broodstock, in preventing streptococcosis in their offspring, via transfer of maternal immunity
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The efficacy of Streptococcus agalactiae vaccine preparations, administered to tilapia broodstock, in preventing streptococcosis in their offspring, via transfer of maternal immunity

机译：通过转移母体免疫，施用于Tilapia Brookstock的链球菌疫苗制剂的疗效疫苗制剂在预防其后代中的链球菌

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This study aims to evaluate the efficacy of Streptococcus agalactiae vaccine preparations, administered to tilapia broodstock, in preventing streptococcosis, through specific and non-specific immunity being transferred to the offspring. The study was conducted in two phases. The first was the vaccination of the broodstock using a whole-cell vaccine, an extracellular product (ECP) vaccine, and a combination of the two with a ratio of 1:1. The vaccines were administered to the broodstock 2 and 3 weeks before spawning. The second phase was the challenge test for larvae produced by vaccinated broodstock, and larvae from the unvaccinated control broodstock, through immersion in a suspension of 10(7) cfu mL(-1) pathogenic S. agalactiae for 30 min, at ages 7, 14, 21, and 28 days post-hatching. The parameters evaluated were the broodstock's blood profile, antibody-lysozyme (in broodstock, eggs, and larvae), and the larvae's relative percent survival. Treatment with the combined vaccine administered 3 weeks before spawning resulted in the broodstock having significantly better antibody levels, lysozyme activity, and hematology profiles, compared to the other treatments (p & 0.05). In addition, the larvae produced by broodstock subjected to this treatment, when challenged with the pathogenic S. agalactiae at ages 7, 14, 21, and 28 days, had RPS values of 95.24, 83.33, 72.22, and 56.02%, respectively. It was concluded that the administration of the "whole-cell/ECP" combination vaccine preparation to tilapia broodstock in the 3 weeks before spawning can increase specific and non-specific immunity in the broodstock and protect the larvae from S. agalactiae infection.
机译：本研究旨在评估链球菌疫苗制剂的疗效，所述疫苗制剂在预防罗非鱼饲养，防止链球菌病，通过特异性和非特异性免疫转移到后代。该研究分两期进行。首先是使用全细胞疫苗，细胞外产物（ECP）疫苗的亲属剂，以及两者的组合，与比例为1：1的疫苗接种。在产卵前2和3周施用疫苗。第二阶段是幼虫通过疫苗接种的幼虫和来自未接种的对照组成的幼虫，通过浸渍在10（7）CFU ml（-1）致病症的悬浮液中浸渍30分钟，在7岁时，阴影后14,21和28天。评估的参数是Broodstock的血液剖面，抗体 - 溶菌酶（在亲和语，鸡蛋和幼虫中），幼虫相对百分比存活。与其他处理相比，用3周施用3周内施用3周的组合疫苗，导致具有明显更好的抗体水平，溶菌酶活性和血液学型材（P＆amp; 0.05）。此外，在7,14,21,21天的致病症急性症状受到攻击时，通过对该处理进行的精灵产生的幼虫分别具有95.24,83.33,72.22和56.02％的RPS值。它的结论是，在产卵前的3周内，将“全细胞/ ECP”组合疫苗制剂给予罗非鱼亲和继力，可以提高家庭植物中的特异性和非特异性免疫，保护幼虫免受嗜虾感染的影响。

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