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Lung imaging - Two dimensional gamma scintigraphy, SPECT, CT and PET

机译:肺部成像-二维伽玛闪烁显像,SPECT,CT和PET

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摘要

This review will cover the principles of imaging the deposition of inhaled drugs and some of the state-of-the art imaging techniques being used today. Aerosol deposition can be imaged and quantified by the addition of a radiolabel to the aerosol formulation. The subsequent imaging of the inhaled deposition pattern can be acquired by different imaging techniques. Specifically, this review will focus on the use of two-dimensional planar, gamma scintigraphy, SPECT, CT and PET.This review will look at how these imaging techniques are used to investigate the mechanisms of drug delivery in the lung and how the lung anatomy and physiology have the potential to alter therapeutic outcomes.
机译:这篇综述将涵盖对吸入药物沉积进行成像的原理以及当今正在使用的一些最新成像技术。可以通过在气溶胶配方中添加放射性标记来对气溶胶沉积进行成像和量化。可以通过不同的成像技术来获取吸入的沉积图案的后续成像。具体而言,本文将重点研究二维平面,γ闪烁显像,SPECT,CT和PET的使用,并探讨这些成像技术如何用于研究药物在肺中的递送机制以及肺部解剖结构和生理学有可能改变治疗效果。

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