Lanthanide-doped upconverting luminescent nanoparticle platforms for optical imaging-guided drug delivery and therapy

ShenJ.; ZhaoL.; HanG.

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Lanthanide-doped upconverting luminescent nanoparticle platforms for optical imaging-guided drug delivery and therapy

机译：镧系元素掺杂的上转换发光纳米粒子平台，用于光学成像引导的药物输送和治疗

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Lanthanide-doped upconverting luminescent nanoparticles (UCNPs) are promising materials for optical imaging-guided drug delivery and therapy due to their unique optical and chemical properties. UCNPs absorb low energy near-infrared (NIR) light and emit high-energy shorter wavelength photons. Their special features allow them to overcome various problems associated with conventional imaging probes and to provide versatility for creating nanoplatforms with both imaging and therapeutic modalities. Here, we discuss several approaches to fabricate and utilize UCNPs for traceable drug delivery and therapy.

机译：镧系元素掺杂的上转换发光纳米粒子（UCNPs）由于其独特的光学和化学特性，是用于光学成像引导药物递送和治疗的有前途的材料。 UCNP吸收低能近红外（NIR）光，并发射高能短波长光子。它们的特殊功能使他们能够克服与常规成像探针相关的各种问题，并为创建具有成像和治疗方式的纳米平台提供了多功能性。在这里，我们讨论了几种制造和利用UCNPs进行可追踪药物输送和治疗的方法。

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《Advanced drug delivery reviews》 |2013年第5期|共12页
作者
ShenJ.; ZhaoL.; HanG.;
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原文格式 PDF
正文语种 eng
中图分类药学;
关键词
Delivery; DNA; Drug; Gene; Imaging; Lanthanide; Nanoparticles; Therapy; Upconversion;

机译：传递;DNA;药物;基因;成像;镧系元素;纳米颗粒;治疗;上转换;

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1. Lanthanide-doped upconverting luminescent nanoparticle platforms for optical imaging-guided drug delivery and therapy [J] . ShenJ., ZhaoL., HanG. Advanced drug delivery reviews . 2013,第5期

机译：镧系元素掺杂的上转换发光纳米粒子平台，用于光学成像引导的药物输送和治疗
2. Upconverting Nanoparticles with a Mesoporous TiO_2 Shell for Near-Infrared-Triggered Drug Delivery and Synergistic Targeted Cancer Therapy [J] . Meili Yin, Enguo Ju, Zhaowei Chen, Chemistry: A European journal . 2014,第43期

机译：具有中孔TiO_2壳的上转换纳米粒子用于近红外触发的药物递送和协同靶向癌症治疗。
3. Near-infrared nanoparticles based on indocyanine green-conjugated albumin: a versatile platform for imaging-guided synergistic tumor chemo-phototherapy with temperature-responsive drug release [J] . Yuxin Ma, Xiaohua Liu, Qianli Ma, OncoTargets and therapy . 2018,第4期

机译：基于吲哚花青绿共轭白蛋白的近红外纳米颗粒：成像指导的协同肿瘤化学光疗，具有温度响应性药物释放的多功能平台
4. Controlled and Localized Drug Delivery Platforms Based on Mussel Adhesive Protein Nanoparticles for Cancer Therapy [C] . Yeonsu Jeong, Yun Kee Jo, Hyung Joon Cha Society for Biomaterials annual meeting and exposition . 2017

机译：基于贻贝粘附蛋白纳米颗粒的可控制的局部药物递送平台，用于癌症治疗
5. The delivery of upconverting phosphors within PEG-protected nanoparticles for NIR-excitable photodynamic therapy and imaging. [D] . Budijono, Stephanie J. 2010

机译：上转换荧光粉在PEG保护的纳米颗粒中的输送，用于近红外激发光动力疗法和成像。
6. Near-infrared nanoparticles based on indocyanine green-conjugated albumin: a versatile platform for imaging-guided synergistic tumor chemo-phototherapy with temperature-responsive drug release [O] . Yuxin Ma, Xiaohua Liu, Qianli Ma, 2018

机译：基于吲哚菁绿共轭白蛋白的近红外纳米粒子：成像指导的协同肿瘤化学光疗法具有温度响应性药物释放的多功能平台
7. Drug Delivery: Engineering Melanin Nanoparticles as an Efficient Drug-Delivery System for Imaging-Guided Chemotherapy (Adv. Mater. 34/2015) [O] . Ruiping Zhang, Quli Fan, Min Yang, 2015

机译：药物递送：工程黑色素纳米粒子作为一种高效的药物输送系统，用于成像化疗（ADV。MART。34/2015）

Lanthanide-doped upconverting luminescent nanoparticle platforms for optical imaging-guided drug delivery and therapy

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