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首页> 外文期刊>Applied biochemistry and biotechnology, Part A. enzyme engineering and biotechnology >Acetylresveratrol as a Potential Substitute for Resveratrol Dragged the Toxic Aldehyde to Inhibit the Mutation of Mitochondrial DNA
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Acetylresveratrol as a Potential Substitute for Resveratrol Dragged the Toxic Aldehyde to Inhibit the Mutation of Mitochondrial DNA

机译：作为白藜芦醇的潜在替代品作为白藜芦醇的潜在替代品拖动毒性醛以抑制线粒体DNA的突变

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The aim of this study was to explore whether or not acetylresveratrol as a potential substitute for resveratrol dragged the toxic aldehyde to inhibit the mutation of mitochondrial DNA. The results revealed that the acetylresveratrol shifted ultraviolet peak of trans-crotonaldehyde from 316 to 311 nm. In mitochondria, the acetylresveratrol split the ultraviolet peak at 311 nm of trans-crotonaldehyde into 311 nm and 309 nm; the aldehyde Raman band of trans-crotonaldehyde was red shifted by the acetylresveratrol from 1689 to 1686 cm(-1) with obvious band decline; Raman bands at 1149 cm(-1), 1168 cm(-1), and 1325 cm(-1) of acetylresveratrol disappeared. In aldehyde dehydrogenase, the aldehyde Raman band of trans-crotonaldehyde was red shifted by the acetylresveratrol from 1689 to 1684 cm(-1) with band decline; Raman bands at 1150 cm(-1), 1168 cm(-1), and 1324 cm(-1) of acetylresveratrol declined. The weak acidic microenvironment was the best, for the acetylresveratrol dragged the toxic aldehyde of trans-crotonaldehyde. Compared with the resveratrol, the effect of the acetylresveratrol on the toxic aldehyde of trans-crotonaldehyde was very similar to that of the resveratrol. The acetylresveratrol is very suitable as a potential substitute for resveratrol dragged the toxic aldehyde to inhibit the mutation of mitochondrial DNA.
机译：本研究的目的是探讨乙酰丙烯酸糖醇是否作为白藜芦醇的潜在替代品拖动毒性醛以抑制线粒体DNA的突变。结果表明，乙酰丙烯酸甘露糖醇从316-311nm移位转歧串醛的紫外峰。在线粒体中，乙酰丙烯酸糖醇将紫外峰分裂为311nm的转歧醛醛至311nm和309nm;通过1689至1686cm（-1）的乙酰丙烯酸甘露糖醛醛旋转的醛醛叶醛与明显的带下降; 1149厘米（-1），1168厘米（-1）和1325厘米（-1）的拉曼带消失。在醛脱氢酶中，通过1689至1684cm（-1）的乙酰丙烯酰醇的醛拉曼带是红色的，带有带下降的红色; 1150厘米（-1），1168厘米（-1）和1324cm（-1）的拉曼带均下降。弱酸性微环境是最好的，对于乙酰丙烯酸糖醇拖动毒性克拉特醛的毒性醛。与白藜芦醇相比，乙酰丙烯酸甘露糖醇对转歧律师的有毒醛的影响与白藜芦醇的毒性非常相似。乙酰丙烯酸糖醇非常适合作为白藜芦醇的潜在替代品拖动毒性醛以抑制线粒体DNA的突变。

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