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首页> 外文期刊>Archives of gynecology and obstetrics. >The risk of placenta previa and cesarean section associated with a thin endometrial thickness: a retrospective study of 5251 singleton births during frozen embryo transfer in China
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The risk of placenta previa and cesarean section associated with a thin endometrial thickness: a retrospective study of 5251 singleton births during frozen embryo transfer in China

机译:胎盘PREVIA和剖宫产的风险与薄子宫内膜厚度相关:在中国冷冻胚胎转移期间的5251单身诞生回顾性研究

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Purpose To determine whether the endometrial thickness (EMT) affects the occurrence of obstetric complications and neonatal outcomes in frozen embryo transfer (FET). Methods We conducted a retrospective study that included singleton deliveries (N = 5251) resulting from FET in a single center between August 2013 and March 2016. Obstetric complications and neonatal outcomes were compared among patients with different EMTs, which were measured the day before embryo thawing. The women were divided into three groups based on the EMT: group 1: 12 mm. Multiple logistic regression and subgroup analyses were performed to determine the potential confounding factors. Results The incidence of placenta previa in groups 1, 2, and 3 was 3.8, 1.0 and 0.5%, respectively, and that of cesarean section was 87.0, 78.3 and 72.0%, respectively (both P < 0.001). The gestational age and birth weight increased from group 1 to group 3 (both P < 0.001). After adjusting for confounders, a thicker EMT was found to be associated with a decreased risk of placenta previa (adjusted odds ratio (aOR) 0.798; 95% confidence interval (95% CI) 0.651-0.979; P = 0.031) and with a decreased risk of cesarean section (aOR 0.926; 95% CI 0.889-0.965; P < 0.001). Regarding the incidence of placenta previa, compared to women in group 3, women in group 1 had an aOR of 6.208 (95% CI 2.169-17.766; P = 0.001), and women in group 2 had an aOR of 1.862 (95% CI 0.851-4.076; P = 0.120). Regarding the incidence of cesarean section, compared to women in group 3, women in group 1 had an aOR of 2.111 (95% CI 1.415-3.455; P < 0.001), and women in group 2 had an aOR of 1.293 (95% CI 1.128-1.481; P < 0.001). Subgroup analyses showed similar results. Conclusions Our results demonstrate that a thin endometrial lining is associated with adverse obstetric and neonatal outcomes and might be related to poor placentation.
机译:目的判断子宫内膜厚度(EMT)是否会影响被冻结胚胎转移(FET)的产科并发症和新生儿结果的发生。方法进行了一项回顾性研究,其中包括FET在2013年8月至2016年3月之间的单一中心中的FET产生的单身交付(n = 5251)。在不同EMT的患者中将产科并发症和新生儿结果进行比较,这是胚胎前一天测量的。基于EMT的女性分为三组:第1组:12毫米。进行多元逻辑回归和亚组分析以确定潜在的混杂因素。结果分别为3,2和3组胎盘PREVIA的发病率为3.8,1.0和0.5%,分别为87.0,78.3和72.0%(P <0.001)。妊娠年龄和出生体重从第1组增加到第3组(P <0.001)。在调整混凝剂后,发现厚度的EMT与胎盘的胎盘风险降低(调整后的差距(AOR)0.798; 95%置信区间(95%CI)0.651-0.979; p = 0.031)并减少剖宫产风险(AOR 0.926; 95%CI 0.889-0.965; P <0.001)。关于PREVIA的发病率,与第3组妇女相比,第1组的妇女有一个6.208的AOR(95%CI 2.169-17.766; p = 0.001),第2组的女性有1.862(95%CI) 0.851-4.076; p = 0.120)。关于剖宫产的发病率,与第3组妇女相比,第1组的妇女的AOR为2.111(95%CI 1.415-3.455; P <0.001),第2组的女性有1.293的AOR(95%CI) 1.128-1.481; p <0.001)。子组分析显示出类似的结果。结论我们的结果表明,薄的子宫内膜衬里与不良产科和新生儿结果有关,并且可能与寄闭差有关。

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