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Risk of adverse pregnancy outcomes by pre-pregnancy Body Mass Index among Italian population: a retrospective population-based cohort study on 27,807 deliveries

机译:意大利人口前妊娠体重指数的不良妊娠危险风险:一项关于27,807分娩的回顾性群体队列研究

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PurposeTo estimate the impact of increasing pre-pregnancy Body Mass Index (BMI) on the risk of adverse maternal and perinatal outcomes, in patients who delivered in an Italian tertiary care Obstetric department.MethodsData, related to women who delivered at Sant'Anna Hospital, Turin, between 2011 and 2015, were collected retrospectively from the hospital database. According to BMI, women were considered as normal weight, overweight, and class 1, 2 and 3 obese (WHO criteria). Logistic regression analysis studied the impact of BMI on maternal and neonatal outcomes, adjusting results for maternal age and parity. Adjusted absolute risks of each outcome were reported according to incremental values in pre-pregnancy BMI.ResultsA total of 27,807 women were included. 75.8% of pregnancies occurred among normal-weight women, whereas 16.7% were overweight, and 7.5% obese women (5.4% class 1, 1.7% class 2 and 0.4% class 3). A 10% decrease in pre-pregnancy BMI was associated with a reduction of at least 15% of Gestational diabetes mellitus (GDM), preeclampsia, maternal admission to intensive care unit (ICU), macrosomia, APGAR 5 < 6 and neonatal admission to ICU. GDM and preeclampsia resulted in the highest reduction being almost 30%. Larger differences in BMI (20-25%) corresponded to at least a 10% in reduction of risk of preterm and very preterm delivery and emergency cesarean section. Differences in maternal pre-pregnancy BMI had no impact on the frequency of shoulder dystocia and stillbirth.ConclusionsThis study offers a quantitative estimation of negative impact of pre-pregnancy obesity on the most common pregnancy and perinatal complications.
机译:purposeto估计在意大利第三节护理产科部门交付的患者中,患有增加的妊娠前体重指数(BMI)对不良孕产妇和围产期结果的影响..在意大利第三级护理产科部门.THODSDATA,与在桑坦娜医院交付的妇女有关,都灵在2011年和2015年间,从医院数据库中回顾性地收集。根据BMI的说法,女性被认为是正常体重,超重和1级,2和3级肥胖(谁标准)。 Logistic回归分析研究了BMI对母体和新生儿结果的影响,调整产妇年龄和平价的结果。根据怀孕前的增量值,报告了每种结果的调整后的绝对风险。审查总共27,807名妇女。妊娠的75.8%发生在正常妇女中,而16.7%的妊娠超重,7.5%肥胖的妇女(5.4%1,1.7%2级和0.4%3级)。妊娠前的10%降低与减少至少15%的妊娠期糖尿病(GDM),前普拉姆,孕产妇入学,重症监护单位(ICU),麦科瘤,APGAR 5 <6和新生儿入院的妊娠期糖尿病(GDM)减少。 GDM和Preclampsia导致最高减少近30%。 BMI(20-25%)的较大差异相当于降低早产和非常早产的风险和急诊剖宫产风险的至少10%。孕产妇前妊娠BMI对肩腹部和脱盐的频率没有影响。结论,研究提供了对妊娠前肥胖的负面影响的定量估计对最常见的妊娠和围产期并发症。

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