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首页> 外文期刊>Archives of disease in childhood. Fetal and neonatal edition >UK recommendations for combating antimicrobial resisitance: a review pf antimicrobial stewardship: systems and processes for effective antimicrobial medicine use( NICEguideline NG15, 2015) and related guidance
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UK recommendations for combating antimicrobial resisitance: a review pf antimicrobial stewardship: systems and processes for effective antimicrobial medicine use( NICEguideline NG15, 2015) and related guidance

机译：英国对抗抗菌栖息的建议：审查PF抗菌管理：有效抗菌药物使用的系统和工艺（NiceGuideline NG15，2015）和相关指导

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BACKGROUND Antimicrobial resistance (AMR) is a major health threat. In 2011, the UK's chief medical officer's annual report described AMR as an 'apocalyptic scenario'1 in which common infections would become untreatable, and young children, arguably the most susceptible to infectious disease, would bear the burden. The problem is caused by overuse and misuse of antibiotics resulting in the survival and spread of resistant bacteria. A recently published review on AMR (2016), outlines the enormity of the problem: 'by 2050, 10million lives a year... are at risk due to the rise of drug-resistant infections if we do not find proactive solutions now. Even today, 7 00 000 people die of resistant infections every year'. The clinician plays a major role in one of the identified solutions: antimicrobial stewardship to preserve drug effectiveness (box 1). This can be a particular challenge in paediatrics: a feverish child may have a serious bacterial infection, almost impossible—at first—to distinguish from a self-limiting viral infection. In neonates, sepsis can be particularly difficult to identity; therefore, in both cases, antibiotics are often given as a precautionary measure.
机译：背景技术抗微生物抗性（AMR）是一个主要的健康威胁。 2011年，英国首席医务人员的年度报告将AMR描述为“世界末日的情景”，其中常见感染将变得无法治愈，幼儿可以是最容易感染性疾病的患者。问题是通过过度使用和滥用抗生素引起的，导致抗性细菌的存活率和扩散。最近发表于关于AMR（2016）的综述，概述了问题的巨大性：'到2050年，如果我们现在没有找到耐药性感染的损害，每年有10万人的生活。即使今天，7 00000人每年都会死于抗性感染。临床医生在其中一个识别的解决方案中发挥着重要作用：抗微生物管道以保护药物效果（盒子1）。这可能是儿科的特殊挑战：发烧的孩子可能具有严重的细菌感染，几乎不可能 - 首先区分自我限制的病毒感染。在新生儿中，败血症可以特别难以身份;因此，在这两种情况下，通常给予抗生素作为预防措施。

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