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首页> 外文期刊>Arthritis & rheumatology. >The Incidence and Prevalence of Systemic Lupus Erythematosus in New York County (Manhattan), New York: The Manhattan Lupus Surveillance Program
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The Incidence and Prevalence of Systemic Lupus Erythematosus in New York County (Manhattan), New York: The Manhattan Lupus Surveillance Program

机译：纽约县（曼哈顿）系统性狼疮红斑狼疮的发病率和患病率：曼哈顿卢普斯监督计划

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Objective The Manhattan Lupus Surveillance Program (MLSP) is a population‐based registry designed to determine the prevalence of systemic lupus erythematosus (SLE) in 2007 and the incidence from 2007 to 2009 among residents of New York County (Manhattan), New York, and to characterize cases by race/ethnicity, including Asians and Hispanics, for whom data are lacking. Methods We identified possible SLE cases from hospital records, rheumatologist records, and administrative databases. Cases were defined according to the American College of Rheumatology (ACR) classification criteria, the Systemic Lupus International Collaborating Clinics (SLICC) classification criteria, or the treating rheumatologist's diagnosis. Rates among Manhattan residents were age‐standardized, and capture–recapture analyses were conducted to assess case underascertainment. Results By the ACR definition, the age‐standardized prevalence and incidence rates of SLE were 62.2 and 4.6 per 100,000 person‐years, respectively. Rates were ～9 times higher in women than in men for prevalence (107.4 versus 12.5) and incidence (7.9 versus 1.0). Compared with non‐Hispanic white women (64.3), prevalence was higher among non‐Hispanic black (210.9), Hispanic (138.3), and non‐Hispanic Asian (91.2) women. Incidence rates were higher among non‐Hispanic black women (15.7) compared with non‐Hispanic Asian (6.6), Hispanic (6.5), and non‐Hispanic white (6.5) women. Capture–recapture adjustment increased the prevalence and incidence rates (75.9 and 6.0, respectively). Alternate SLE definitions without capture–recapture adjustment revealed higher age‐standardized prevalence and incidence rates (73.8 and 6.2, respectively, by the SLICC definition and 72.6 and 5.0 by the rheumatologist definition) than the ACR definition, with similar patterns by sex and race/ethnicity. Conclusion The MLSP confirms findings from other registries on disparities by sex and race/ethnicity, provides new estimates among Asians and Hispanics, and provides estimates using the SLICC criteria.
机译：目的曼哈顿狼疮监察计划（MLSP）是一种基于人口的注册表旨在确定系统性红斑狼疮（SLE）的2007年患病率和2007年至2009年纽约县（曼哈顿），纽约居民中的发生率，并按种族/族裔，包括亚裔和西班牙裔，对他们来说，数据缺乏表征的情况。方法我们确定了医院记录，风湿病记录和管理数据库可能SLE病例。例根据美国风湿病学院（ACR）的分类标准，系统性国际合作诊所（SLICC）分类标准，或所述处理风湿病的诊断定义。曼哈顿居民率年龄标准化，并进行了捕获 - 再捕获分析，评估情况underascertainment。结果由ACR定义，SLE的年龄标化患病率和发病率分别为62.2和4.6每10万人年。率较高〜9倍，女性比男性发病为（107.4对12.5）和发病率（7.9比1.0）。与非西班牙裔白人妇女（64.3）相比，患病率之间的非西班牙裔黑人（210.9），西班牙（138.3）高，非西班牙裔亚洲（91.2）的女性。发病率是非西班牙裔黑人女性（15.7）与非西班牙裔亚洲（6.6），西班牙（6.5），和非西班牙裔白人（6.5）比女性更高之中。捕获 - 再捕获调整增加的患病率和发病率（75.9和6.0，分别地）。没有捕获 - 再调整替代SLE的定义揭示了比ACR清晰度更高年龄标化患病率和发病率（73.8和6.2，分别由SLICC定义，72.6和5.0由风湿病的定义），按性别和种族类似的模式/种族。结论MLSP从其他登记上的差距按性别和种族/族裔证实研究结果，提供了亚裔和西班牙裔新的估计，并提供了使用SLICC标准估算。

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