• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Artificial Organs >Evolution of pediatric ventricular assist devices and their neurologic and renal complications-A 24-year single-center experience
【24h】

Evolution of pediatric ventricular assist devices and their neurologic and renal complications-A 24-year single-center experience

机译：小儿心室辅助装置的演变及其神经系统和肾复发 - 24年的单中心经验

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Utilization of ventricular assist devices (VADs) in adult populations with severe heart failure as a bridge to transplant has become the standard of care over the past two decades. Analogously, the use of VADs in pediatric populations has become more commonplace as pediatric heart transplantation has become more prevalent. We still have much to learn, however, about the complications after VAD placement in pediatric patients, their impact on transplantation and, in particular, how outcomes have changed over time. The objectives of this study were to (a) review the experience of a single pediatric VAD center, (b) identify risk factors that could lead to poor outcomes in patients on the transplant waitlist after VAD implantation and (c) demonstrate changes in outcomes over time. A retrospective cohort analysis was performed comparing death as a primary outcome and stroke and acute kidney injury (AKI) as secondary outcomes, across the study period divided into three timed eras. We analyzed 88 patients supported by a VAD over a 24-year timeframe. The duration, age at implant and indication for VAD support did not change significantly across the eras. We found that the incidence of stroke decreased over the study period and, while the rates of AKI did not change over the study period, those who developed AKI, while supported on VAD, had an increased risk of death.
机译：在成年人群中使用心室辅助装置（VADS）与严重心力衰竭作为移植桥的成人群体已成为过去二十年的护理标准。类似地，随着儿科心脏移植变得更加普遍，使用VAD在儿科人群中的使用变得更加普遍。然而，我们仍然有很大的学习，然而，在小儿患者中展示中的复发后，它们对移植的影响以及结果如何随着时间的推移而变化。本研究的目标是（a）审查单个儿科VAD中心的经验，（b）识别在VAD植入和（c）后移植候补者在移植候补欲绝的患者中可能导致患者的危险因素展示结果时间。在研究期间将死亡作为主要结果和中风和急性肾脏损伤（AKI）进行了初步结果进行了回顾性的群组分析，横跨了研究期间分为三个定时时代。我们分析了88名由VAD支持的患者，超过24年的时间框架。植入物的持续时间和VAD支持的指示在时代没有显着变化。我们发现，中风的发生率降低了研究期，而AKI的率没有改变研究期间，那些开发AKI的人，同时支持VAD，导致死亡风险增加。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号