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首页> 外文期刊>Artificial Organs >Hemodynamic Performance of a New Punched Stent Strut: A Numerical Study
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Hemodynamic Performance of a New Punched Stent Strut: A Numerical Study

机译：新穿孔支架的血流动力学性能：数值研究

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摘要

Local flow disturbance by arterial stent struts has been shown to play an important role in stent thrombosis. To reduce the local flow disturbance near a stent strut, we proposed a new concept of stent design with small holes in the stent struts. The present study evaluated the new design numerically by comparing it with the traditional stent in terms of local hemodynamic parameters such as flow velocity, flow recirculation area, time-averaged wall shear stress (TAWSS), oscillating shear index (OSI), and relative residence time (RRT). The results demonstrated that when compared with the traditional strut, the new design could significantly enhance flow velocity and reduce the flow recirculation zone in the vicinity of the strut. Moreover, the new design would significantly elevate TAWSS and remarkably reduce OSI and RRT along the host arterial wall. In conclusion, the new design of stent struts with punched holes is advantageous over the traditional one in the aspect of improving local hemodynamics, which may reduce thrombosis formation and promote re-endothelialization after stenting.
机译：动脉支架支柱的局部流动扰动已被证明在支架血栓形成中起重要作用。为了减少支架支柱附近的局部流动障碍，我们提出了一种新的支架设计概念，在支架支柱中的小孔。本研究通过在局部血流动力学参数如流速，流量再循环区域，时间平均壁剪切应力（TAWS），振荡剪切指数（OSI）和相对住宅的局部血流动力学参数，通过将其与传统支架进行比较，通过将其与传统支架进行比较来计算新的设计。时间（RRT）。结果表明，与传统支柱相比，新设计可以显着增强流速，并减少支柱附近的流量再循环区。此外，新设计将显着升高Tawss，并显着减少沿主动脉壁的OSI和RRT。总之，具有穿孔孔的支架支柱的新设计在改善局部血流动力学方面的传统方面是有利的，这可能降低血栓形成形成并在支架后促进重新内皮化。

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  • 来源
    《Artificial Organs》 |2016年第7期|共9页
  • 作者

    Xue Yan; Liu Xiao; Sun Anqiang; Zhang Peng; Fan Yubo; Deng Xiaoyan;

  • 作者单位

    Beihang Univ Minist Educ Sch Biol Sci &

    Med Engn Key Lab Biomech &

    Mechanobiol Beijing Peoples;

    Beihang Univ Minist Educ Sch Biol Sci &

    Med Engn Key Lab Biomech &

    Mechanobiol Beijing Peoples;

    Beihang Univ Minist Educ Sch Biol Sci &

    Med Engn Key Lab Biomech &

    Mechanobiol Beijing Peoples;

    Beihang Univ Minist Educ Sch Biol Sci &

    Med Engn Key Lab Biomech &

    Mechanobiol Beijing Peoples;

    Beihang Univ Minist Educ Sch Biol Sci &

    Med Engn Key Lab Biomech &

    Mechanobiol Beijing Peoples;

    Beihang Univ Minist Educ Sch Biol Sci &

    Med Engn Key Lab Biomech &

    Mechanobiol Beijing Peoples;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 器官移植术;
  • 关键词

    Punched stent strut; Hemodynamics; Stent thrombosis; Endothelialization;

    机译：穿孔支架;血流动力学;支架血栓形成;内皮化;

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