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首页> 外文期刊>Artificial Organs >Plasma Skimming in a Spiral Groove Bearing of a Centrifugal Blood Pump
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Plasma Skimming in a Spiral Groove Bearing of a Centrifugal Blood Pump

机译：在离心血液泵的螺旋槽轴承中的等离子撇渣

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摘要

Plasma skimming is a phenomenon in which discharge hematocrit is lower than feed hematocrit in microvessels. Plasma skimming has been investigated at a bearing gap in a spiral groove bearing (SGB), as this has the potential to prevent hemolysis in the SGB of a blood pump. However, it is not clear whether plasma skimming occurs in a blood pump with the SGB, because the hematocrit has not been obtained. The purpose of this study is to verify plasma skimming in an SGB of a centrifugal blood pump by developing a hematocrit measurement method in an SGB. Erythrocyte observation using a high-speed microscope and a bearing gap measurement using a laser confocal displacement meter was performed five times. In these tests, bovine blood as a working fluid was diluted with autologous plasma to adjust the hematocrit to 1.0%. A resistor was adjusted to achieve a pressure head of 100 mm Hg and a flow rate of 5.0 L/min at a rotational speed of 2800 rpm. Hematocrit on the ridge region in the SGB was measured using an image analysis based on motion image of erythrocytes, mean corpuscular volume, the measured bearing gap, and a cross-sectional area of erythrocyte. Mean hematocrit on the ridge region in the SGB was linearly reduced from 0.97 to 0.07% with the decreasing mean bearing gap from 38 to 21 m when the rotational speed was changed from 2250 to 3000 rpm. A maximum plasma skimming efficiency of 93% was obtained with a gap of 21 m. In conclusion, we succeeded in measuring the hematocrit on the ridge region in the SGB of the blood pump. Hematocrit decreased on the ridge region in the SGB and plasma skimming occurred with a bearing gap of less than 30 m in the hydrodynamically levitated centrifugal blood pump.
机译：等离子体撇渣是一种现象，其中排出血细胞比容低于微血管中的饲料血细胞比容。已经在螺旋槽轴承（SGB）中的轴承间隙上进行了等离子体撇渣，因为这有可能在血液泵的SGB中防止溶血。然而，目前尚不清楚是否在具有SGB的血液泵中发生血浆撇粒，因为血细胞比容尚未获得。本研究的目的是通过在SGB中培养血细胞比容测量方法来验证离心血液泵的SGB中的等离子体撇去。使用高速显微镜和使用激光共焦位移计的轴承间隙测量的红细胞观察五次。在这些测试中，用自体血浆稀释作为工作流体的牛血，以调节血细胞比容至1.0％。调整电阻器以实现100mm Hg的压力头，并且以2800rpm的转速为5.0升/分钟的流速。使用基于红细胞的运动图像的图像分析，平均碎石体积，测量的轴承间隙和红细胞横截面积测量SGB中的脊髓纤维比。在SGB中的脊状区域上的平均血细胞比容从0.97〜0.07％线性地降低，随着旋转速度从2250变为3000rpm时，在38至21μm的情况下，平均轴承间隙的降低。获得的最大等离子体涂上效率为93％，间隙为21米。总之，我们成功地测量了血液泵的SGB中的脊地区上的血细胞比容。血细胞比容器在SGB中的脊区域上降低，并且在流体动力学升高的离心血液泵中，在轴承间隙中发生轴承间隙小于30μm的等离子体脱脂。

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