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首页> 外文期刊>Artificial Organs >Translation of First North American 50 and 70 cc Total Artificial Heart Virtual and Clinical Implantations: Utility of 3D Computed Tomography to Test Fit Devices
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Translation of First North American 50 and 70 cc Total Artificial Heart Virtual and Clinical Implantations: Utility of 3D Computed Tomography to Test Fit Devices

机译：第一个北美50和70CC总人工心脏虚拟和临床植入的翻译：3D计算机断层扫描的效用测试配合装置

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摘要

Since the creation of SynCardia's 50 cc Total Artificial Hearts (TAHs), patients with irreversible biventricular failure now have two sizing options. Herein, a case series of three patients who have undergone successful 50 and 70 cc TAH implantation with complete closure of the chest cavity utilizing preoperative virtual implantation of different sized devices for surgical planning are presented. Computed tomography (CT) images were used for preoperative planning prior to TAH implantation. Three-dimensional (3D) reconstructions of preoperative chest CT images were generated and both 50 and 70 cc TAHs were virtually implanted into patients' thoracic cavities. During the simulation, the TAHs were projected over the native hearts in a similar position to the actual implantation, and the relationship between the devices and the atria, ventricles, chest wall, and diaphragm were assessed. The 3D reconstructed images and virtual modeling were used to simulate and determine for each patient if the 50 or 70 cc TAH would have a higher likelihood of successful implantation without complications. Subsequently, all three patients received clinical implants of the properly sized TAH based on virtual modeling, and their chest cavities were fully closed. This virtual implantation increases our confidence that the selected TAH will better fit within the thoracic cavity allowing for improved surgical outcome. Clinical implantation of the TAHs showed that our virtual modeling was an effective method for determining the correct fit and sizing of 50 and 70 cc TAHs.
机译：自创建Syncardia的50 CC总人造心（TAHS）以来，患有不可逆转的双心性故障的患者现在具有两个尺寸的选择。这里，呈现了利用术前虚拟植入不同尺寸的装置进行外科手术规划的胸腔完全闭合的胸腔的成功50和70cc tah植入的三个患者。计算断层扫描（CT）图像用于在TAH植入之前的术前计划。产生术前胸部CT图像的三维（3D）重建，并且50和70cc Tah两者几乎植入患者的胸腔。在模拟期间，TAHS在与实际植入的类似位置上投射到原生心脏上，并且评估了器件和地区，心室，胸壁和隔膜之间的关系。 3D重建图像和虚拟建模用于模拟和确定每位患者，如果50或70 CC TAH将具有更高的成功植入无需并发症的可能性。随后，所有三名患者根据虚拟建模接受了适当大小的TAH的临床植入物，并且它们的胸腔腔被完全关闭。这种虚拟植入增加了我们的信心，即所选择的TAH将更好地贴合在胸腔内，允许改善手术结果。 TAHS的临床植入表明，我们的虚拟建模是确定50和70 CC TAHS的正确配合和尺寸的有效方法。

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