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Home‐based training using neuromuscular electrical stimulation in patients on continuous ambulatory peritoneal dialysis: A pilot study

机译:在连续动态腹膜透析患者中使用神经肌肉电刺激的家庭培训:试验研究

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Abstract There is ample evidence that maintenance of basic physical fitness through exercise training is crucial for patients with chronic renal insufficiency. Rehabilitation based on neuromuscular electrical stimulation (NMES) of thigh muscles has been shown to have many beneficial effects in patients with chronic diseases. It is likely that NMES could have beneficial effects also in patients on chronic ambulatory peritoneal dialysis (CAPD). NMES was applied for 20?weeks to 14 patients on CAPD, mean age 61.9 (8.7) years, using battery‐powered stimulators (CEFAR‐REHAB X2; Sweden) and self‐adhesive electrodes 80?×?130 mm (PALS Platinum; Denmark). Stimulation characteristics: biphasic current, pulse width 400?μs, 8?seconds contraction‐12?seconds relaxation, frequency modulation 40‐60?Hz, and maximal intensity 60?mA. NMES was home‐based and applied simultaneously to quadriceps muscles of both legs (2 × 30?min/day). Functional performance, muscle power ( F max ), arterial stiffness (assessed by cardio‐ankle vascular index‐CAVI), and quality of life by KDQOL‐SF evaluation was done at baseline and at the end of program. Home NMES improved significantly the main functional parameters: VO 2peak /kg increased by +2.2 (1.6) mL O 2 /kg/min ( P ??0.002), peak workload by +0.1 (0.1) W/kg ( P ??0.005), and distance walked in 6?MWT by +44.7 (58.4) m ( P ??0.008). Only insignificant changes were observed in CAVI and F max . KDQOL‐SF analysis showed significant improvement in seven parameters of QoL ( P ??0.012‐0.049). This pilot study is the first clinical report dealing with the use of NMES in patients on CAPD. The results demonstrate that an improvement of exercise capacity and QoL can be achieved by home‐based NMES in CAPD patients.
机译:摘要有充分的证据表明,通过运动培训维护基本身体健康对慢性肾功能不全的患者至关重要。基于神经肌肉电刺激(NMES)的大腿肌肉的康复已被证明对慢性疾病的患者具有许多有益的效果。在慢性动态腹膜透析(CAPD)的患者中也可能对NMES具有有益效果。纽姆斯申请了20周至第14岁的CAPD患者,平均61.9岁(8.7)年,使用电池供电的刺激器(CEFAR-REHAB X2;瑞典)和自粘电极80?×130mm(PALS铂;丹麦)。刺激特性:双相电流,脉冲宽400?μs,8?秒收缩-12?秒弛豫,频率调制40-60?Hz,最大强度60?ma。 NMES是基于家庭的,同时应用于两条腿的Quadriceps肌肉(2×30?min /日)。功能性能,肌肉力量(F MAX),动脉僵硬度(Cardio-踝血管指数-Cavi评估)以及KDQOL-SF评估的生命质量在基线和方案结束时完成。家庭NMES显着改善了主要功能参数:VO 2PEAK / kg增加+ 2.2(1.6)ml O 2 / kg / min(p≤x0.002),峰值工作量+0.1(0.1)w / kg(p? & 0.005),距离在6℃+ 44.7(58.4)m(p≤≤0.008)。在Cavi和F Max中只观察到微不足道的变化。 KDQol-SF分析显示出七个参数的QOL(p≤≤0.012-0.049)的显着改善。该试点研究是第一份处理CAPD患者使用NMES的临床报告。结果表明,CAPD患者中的家庭纽姆斯可以提高运动能力和QOL。

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