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首页> 外文期刊>Acta Radiologica >Enhanced computed tomography or magnetic resonance imaging: a choice between contrast medium-induced nephropathy and nephrogenic systemic fibrosis?
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Enhanced computed tomography or magnetic resonance imaging: a choice between contrast medium-induced nephropathy and nephrogenic systemic fibrosis?

机译：增强型计算机断层扫描或磁共振成像：在造影剂诱发的肾病和肾源性系统性纤维化之间进行选择？

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For more than 10 years, it has been believed that it would be better for the kidneys if patients with reduced renal function were referred to enhanced magnetic resonance imaging (MRI) rather than undergoing radiography (e.g., arteriography, computed tomography [CTj) with iodinated contrast media (CM) (20). It may indeed be better for the kidneys, but recently it has been shown that it may be associated with another severe adverse reaction: a potentially disabling and life-threatening disease, nephrogenic systemic fibrosis (NSF), may occur in the weeks following exposure to certain extracellular gadolinium-based contrast media (13, 19). Thus, a patient with reduced renal function (chronic kidney disease [CKD] stage 4 and 5: glomerular filtration rate [GFR] <30 ml/min) faces the unpleasant choice of risking contrast medium-induced nephropathy (CIN) after administration of iodine-based CM or NSF after exposure to gadolinium-based CM (17).
机译：十多年来，人们认为，将肾功能不全的患者转诊至增强磁共振成像（MRI）而不是接受碘化放射线照相（例如，动脉造影，计算机断层扫描[CTj]）对肾脏会更好。造影剂（CM）（20）。对于肾脏来说确实可能更好，但是最近已经证明它可能与另一种严重的不良反应有关：暴露于皮肤的几周内可能会发生潜在的致死性和威胁生命的疾病，即肾源性系统性纤维化（NSF）。某些基于细胞extra的造影剂（13、19）。因此，肾功能减退（慢性肾脏病[CKD] 4和5期：肾小球滤过率[GFR] <30 ml / min）的患者在服用碘后面临危险，选择服用造影剂诱发的肾病（CIN）暴露于g基CM的基础上的CM或NSF（17）。

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