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首页> 外文期刊>Archivos Latinoamericanos de Nutricion >Nutritional supplements as modifiers of morbidity and mortality in cancer patients
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Nutritional supplements as modifiers of morbidity and mortality in cancer patients

机译：营养补充剂作为癌症患者的发病率和死亡率的改性剂

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Cachexia, a multifactorial syndrome characterized by the loss of skeletal muscle mass with or without loss of fat mass that cannot be reversed by conventional nutrition support, is frequently present in patients with chronic diseases such as cancer, in whom the health status deteriorates markedly. The objective of this review was to study the impact of nutritional supplements on morbidity and mortality of patients with cachexia secondary to cancer. A literature search was conducted (Embase and Medline-Pubmed) looking for references that described associations between supplements and morbidity or mortality in patients with cachexia secondary to cancer. Non-systematic literature reviews, or studies with other non-clinical outcomes were excluded. A total of 42 articles were selected, and their full text version reviewed. We found that polyunsaturated fatty acids increase body weight; antioxidants reduce cancer progression; selenium, zinc, iron and copper improve the immune system and proteins and caloric supplements prevent lipolysis and proteolysis. Within the limitations of the study is the reference to multiple types of cancer, which in themselves present significant differences in treatment and prognosis of patients. As a conclusion, nutritional support with nutritional supplements containing polyunsaturated fatty acids (EPA-DHA), micronutrients (Zn, Se, Cu, Fe, vitamins C and E) and amino acids (l-arginine, l-glutamine and b hidroxymethylbutyrate), can improve morbimortality and therefore quality of life in patients with cachexia secondary to cancer.
机译：CaChexia，一种多因素综合征，其特征在于患骨骼肌损失的骨骼肌损失或不通过常规营养支持不能逆转的脂肪质量损失，通常存在于患有癌症的慢性疾病（如癌症）的患者中，健康状况显着恶化。本综述的目的是研究营养补充剂对癌症患者患者的发病率和死亡率的影响。进行了文献搜索（开设和Medline-Pubmed）寻找描述的参考文献，所述参考文献描述了癌症患者患者的补充剂和发病率或死亡率之间的关联。不包括非系统文献审查或其他非临床结果的研究被排除在外。共选出42篇文章，并审核了他们的全文版本。我们发现多不饱和脂肪酸增加体重;抗氧化剂减少癌症进展;硒，锌，钢铁和铜改善免疫系统和蛋白质和热量补充，可防止脂解和蛋白水解。在研究的局限内，是对多种癌症的参考，其本身本身存在患者治疗和预后的显着差异。作为结论，营养补充剂含有多不饱和脂肪酸（EPA-DHA），微量营养素（Zn，Se，Cu，Fe，维生素C和E）和氨基酸（L-精氨酸，L-谷氨酰胺和B HIDroxymethylyrate），可以提高病情，因此患有癌症患者的生长患者的生活质量。

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