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首页> 外文期刊>Aviation, space, and environmental medicine. >[146] MELANOMA: AN AEROMEDICAL UPDATE
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[146] MELANOMA: AN AEROMEDICAL UPDATE

机译：[146]黑色素瘤：一个航空医学更新

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MOTIVATION: Melanoma is the most serious and fatal form of skin cancer given its propensity for rapid spread to other parts of the body. Significant aeromedical concern surrounds the potential for metastatic spread in this disease that must be addressed prior to returning an aviator to the cockpit. OVERVIEW: Survival and disease recurrence risk for aviators with melanoma will largely depend on the stage of disease at time of diagnosis. Localized cutaneous melanoma includes Stage 0 (in situ melanoma), Stage I, and Stage II disease. Stage III melanoma is defined by the presence of regional nodal disease, and Stage IV melanoma is characterized by distant metastatic disease. Individuals with thin stage I melanoma are likely to have prolonged disease-free survival, while those with later Stage II to IV melanoma are at significantly increased risk of metastatic disease spread and death.
机译：动机：黑色素瘤是皮肤癌最严重和致命的致命形式，鉴于其快速扩散到身体的其他部位的倾向。 显着的航空医学关注围绕在将飞行员返回到驾驶舱之前必须解决的这种疾病中的转移性传播的可能性。 概述：具有黑素瘤的患者的存活和疾病复发风险将在诊断时主要取决于疾病阶段。 局部皮肤黑素瘤包括第0阶段（原位黑色素瘤），阶段I和阶段II疾病。 III阶段的黑色素瘤由区域节点疾病的存在定义，并且阶段的MELANOMA是具有远方转移性疾病的特征。 具有薄阶段的Melanoma的个体可能会延长疾病存活，而那些与IV Selanoma的后期阶段II阶段的患者显着增加转移性疾病的风险和死亡。

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