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首页> 外文期刊>Acta Radiologica >Cardiac output measured by electrical velocimetry in the CT suite correlates with coronary artery enhancement: a feasibility study.
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Cardiac output measured by electrical velocimetry in the CT suite correlates with coronary artery enhancement: a feasibility study.

机译：通过CT套件中的测速仪测量的心输出量与冠状动脉增强相关：一项可行性研究。

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BACKGROUND: Cardiac output (CO) is inversely related to vascular contrast medium (CM) enhancement during computed tomography (CT). Impedance cardiography with a new technique, electrical velocimetry (EV), may create opportunities to measure CO pre-examination for adaptation of CM injection parameters. PURPOSE: To relate CO(EV) measured by radiology staff to aortic attenuation as a measure of coronary artery attenuation during CT coronary angiography (CTCA), and to formulate a tentative statistical model to adapt CM injection parameters to CO. MATERIAL AND METHODS: CO(EV) was measured immediately before 100 kVp CTCA (64-multirow detector) in 27 patients with presumed coronary artery disease. For CTCA, 260 mg I/kg (maximum dosage weight: 80/90 kg for women/men) was injected intravenously during 12 s. Simple linear regression analysis was performed to explore the correlation between aortic attenuation (Hounsfield units, HU) and body weight, the influence of CO(EV) on aortic attenuation adjusted to injected CM dose rate (HU per mg I/kg/s), and to establish a tentative formula on how to adapt CM injection parameters to CO(EV) and desired aortic attenuation. RESULTS: The correlation between aortic attenuation and body weight was weak and non-significant (r=-0.14 after outlier exclusion). A significant negative correlation (r=-0.63) was found between aortic attenuation adjusted to injected CM dose rate (HU per mg I/kg/s) and CO(EV). The resulting formula, CM dose rate=CO(EV)x(aortic attenuation-240)/55, made it possible to calculate CM volumes and injection rates at various COs and, for example, the present mean aortic attenuation (438 HU), injection time (12 s), CM concentration (320 mg I/ml), and a certain body weight. CONCLUSION: EV makes it possible to measure CO in the CT suite before vascular examinations. Hence, CM doses may be decreased in low CO states to reduce the risk of CM-induced nephropathy without jeopardizing diagnostic quality and may be increased in high CO states to avoid poor enhancement.
机译：背景：在计算机断层扫描（CT）期间，心输出量（CO）与血管造影剂（CM）增强成反比。阻抗心动图具有一种新技术，即电子测速（EV），可以创造机会来测量CO预检查以适应CM注射参数。目的：将放射科工作人员测得的CO（EV）与主动脉衰减联系起来，以作为CT冠状动脉造影（CTCA）期间冠状动脉衰减的量度，并建立一个初步的统计模型以使CM注射参数适应CO。 （EV）是在100 kVp CTCA（64多行检测器）之前立即对27例冠状动脉疾病患者进行测量的。对于CTCA，在12 s内静脉注射260 mg I / kg（最大剂量重量：女性为80/90 kg）。进行了简单的线性回归分析，以探索主动脉衰减（Hounsfield单位，HU）与体重之间的相关性，并根据注入的CM剂量率（HU每毫克I / kg / s）调整CO（EV）对主动脉衰减的影响，并建立关于如何使CM注入参数适应CO（EV）和所需主动脉衰减的初步公式。结果：主动脉衰减与体重之间的相关性较弱且无统计学意义（在排除异常值后，r = -0.14）。在调整为注射的CM剂量率（HU每毫克I / kg / s）和CO（EV）之间，发现主动脉衰减之间存在显着的负相关（r = -0.63）。所得的公式CM剂量率= CO（EV）x（主动脉衰减-240）/ 55使计算各种CO时的CM体积和注射速率成为可能，例如，当前平均主动脉衰减（438 HU），注射时间（12 s），CM浓度（320 mg I / ml）和一定体重。结论：EV使在进行血管检查之前在CT套件中测量CO成为可能。因此，在低CO状态下可降低CM剂量，以降低CM引起的肾病的风险，而不会损害诊断质量，而在高CO状态下可增加CM剂量，以免增强效果差。

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