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首页> 外文期刊>Acta Radiologica >MRI-guided percutaneous laser ablation of small renal cell carcinoma: Initial clinical experience.
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MRI-guided percutaneous laser ablation of small renal cell carcinoma: Initial clinical experience.

机译：MRI指导的小肾细胞癌经皮激光消融术：初步临床经验。

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BACKGROUND: The number of detected small renal cell carcinomas (RCCs) has been rising, largely due to advances in imaging. Open surgical resection is the standard management of small RCCs; however, imaging-guided percutaneous ablative therapies have emerged as a minimally invasive treatment alternative, especially for patients who are poor candidates for surgery. PURPOSE: To evaluate the initial clinical experience of magnetic resonance imaging (MRI)-guided percutaneous laser ablation of small RCCs. MATERIAL AND METHODS: Eight patients with 10 tumors were treated with percutaneous MRI-guided laser ablation. All tumors (diameter range 1.5-3.8 cm, mean 2.7 cm) were biopsy-proven RCCs. By using a 0.23 T open MRI system and general anesthesia in patients, one to four (mean 2.6) laser fibers were placed and the tumors were ablated under near real-time MRI control by observing the signal void caused by the temperature change in the heated tissue. The treatment was considered successful if the tumor showed no contrast enhancement at follow-up imaging. RESULTS: All except one tumor were successfully ablated in one session. The first patient treated showed enhancing residual tumor in post-procedural MRI; she has thus far declined retreatment. One complication, a myocardial infarction, occurred; all other patients tolerated the procedure well. No local recurrence was discovered during the follow-up (range 12-30 months, mean 20 months). CONCLUSION: In this small group of patients with relatively short follow-up period, MRI-guided percutaneous laser ablation proved to be a promising treatment option for small RCCs.
机译：背景：检测到的小肾细胞癌（RCC）的数量一直在增加，这主要是由于成像技术的进步。开放式手术切除是小型RCC的标准管理方法。然而，影像引导的经皮消融治疗已成为一种微创治疗替代方案，特别是对于那些不适合手术的患者。目的：评估磁共振成像（MRI）引导的小型RCC经皮激光消融的初步临床经验。材料与方法：8例10个肿瘤的患者接受了经皮MRI引导的激光消融治疗。所有肿瘤（直径范围1.5-3.8 cm，平均2.7 cm）均经活检证实为RCC。通过使用0.23 T开放式MRI系统并在患者全身麻醉下，放置一到四根（平均2.6根）激光纤维，并在近实时MRI控制下通过观察由加热温度变化引起的信号空洞消融肿瘤组织。如果肿瘤在后续影像学检查中未显示对比度增强，则认为该治疗成功。结果：除一个肿瘤外，所有其他肿瘤均在一个疗程中成功消融。首例接受治疗的患者在术后MRI中显示出残留肿瘤的增强;迄今为止，她一直拒绝接受治疗。发生了一种并发症，即心肌梗塞;所有其他患者对手术均耐受良好。在随访期间（12-30个月，平均20个月）未发现局部复发。结论：在这一小部分随访时间相对较短的患者中，MRI引导的经皮激光消融被证明是小型RCC的有前途的治疗选择。

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